YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: M2K6_ARATH

General Information:
Name(s) found: M2K6_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
SHOW ALL
  • Mitogen-activated protein kinase kinase 6 OS=Arabidopsis thaliana GN=MKK6 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 356 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein amino acid phosphorylation [IEA]
    Molecular Function: MAP kinase kinase activity [IDA][TAS]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKIKSNLKQ LKLSVPAQES PISSFLTASG TFHDGDFLLN QKGLRLTSDE KQSRQSDSKE  60
   61 LDFEITAEDL ETVKVIGKGS GGVVQLVRHK WVGKFFAMKV IQMNIQEEIR KQIVQELKIN 120
  121 QASSQCPHVV VCYHSFYHNG AFSLVLEYMD RGSLADVIRQ VKTILEPYLA VVCKQVLLGL 180
  181 VYLHNERHVI HRDIKPSNLL VNHKGEVKIS DFGVSASLAS SMGQRDTFVG TYNYMSPERI 240
  241 SGSTYDYSSD IWSLGMSVLE CAIGRFPYLE SEDQQNPPSF YELLAAIVEN PPPTAPSDQF 300
  301 SPEFCSFVSA CIQKDPPARA SSLDLLSHPF IKKFEDKDID LGILVGTLEP PVNYLR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..356] PSI-BLAST 50.045757 X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • transferase activity
    		•  2.34875558765742 bayes_pls_golite062009
  • protein binding
    		•  2.276111749106 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  2.26064543790212 bayes_pls_golite062009
  • tubulin binding
    		•  2.18641675163967 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • MAP kinase 2 activity
    		•  1.93464174962664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • microtubule binding
    		•  1.88110801192607 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.7769021678395 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.6878868450299 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • receptor activity
    		•  1.57112777506542 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.56748951434625 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.46547714006072 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.4571078357189 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  1.42275431028856 bayes_pls_golite062009
  • DNA binding
    		•  1.35333135345112 bayes_pls_golite062009
  • kinase binding
    		•  1.26086833316556 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.22172815474021 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  1.21636393741109 bayes_pls_golite062009
  • structural constituent of muscle
    		•  1.19908793854422 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • transcription factor activity
    		•  1.10928254946881 bayes_pls_golite062009
  • protein kinase binding
    		•  1.06030596516506 bayes_pls_golite062009
  • JUN kinase kinase kinase activity
    		•  1.00828610859671 bayes_pls_golite062009
  • receptor binding
    		•  0.990272341309676 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • transcription activator activity
    		•  0.846644791435606 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • JUN kinase kinase kinase kinase activity
    		•  0.736550724014849 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.728507215600658 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.66619998121599 bayes_pls_golite062009
  • protein complex binding
    		•  0.599713385230491 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.537170519944039 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • enzyme binding
    		•  0.46284745266176 bayes_pls_golite062009
  • actin binding
    		•  0.456340967230669 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.451090007290896 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.442502307901785 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.401250804041384 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.35140991120688 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.344522125452779 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  0.26602283402868 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  0.26602283402868 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.205652638854091 bayes_pls_golite062009
  • heparin binding
    		•  0.199071129344272 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  0.158673185759192 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  0.15419076927719 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.150740450460731 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.0795689006739899 bayes_pls_golite062009
  • growth factor binding
    		•  0.0526340287295695 bayes_pls_golite062009
  • PTB domain binding
    		•  0.0449060071013108 bayes_pls_golite062009
  • MAP kinase kinase kinase kinase activity
    		•  0.01826424351081 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle