Protein Overview: old-2

General Information:
Name(s) found:	old-2 / CE03838 [WormBase]
Description(s) found: Found 18 descriptions. SHOW ALL	WBGene00003863 locus:old-2 status:Predicted UniProt:Q23677 protein_id:CAA90147.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	498 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	signal transduction [IEA] determination of adult lifespan [IMP] protein amino acid phosphorylation [IEA]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [IEA] non-membrane spanning protein tyrosine kinase activity [IEA] transmembrane receptor protein tyrosine kinase activator activity [ISS] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGSVIFFAL FSSYCFASCY ARNLTLGRNF EDSFKRVPRA SEKNELGDSN VQQIIFISLY  60
   61 SVFVALAIGI CCLIKAYKSK KRQLPANRSK GNEYLLEPTT ADQKKRYSNN IVPPEPTPYP 120
  121 ITSGEDDFGK TPSRLSNEEC PPELKLAPIN DRIKYLHYYA EVEINEEDLD ISKGRPLGSG 180
  181 EFGIIRKGFL RSKNSKNKET ESRLEVAVKS PLNEYNHIQQ ELIYDELKVM CAVGKHPNIL 240
  241 ALVGGITIGE KRMIISELVE NGDLLSFLRK NRRNFTIDQL AFEPEKPSLG LVDLVSFAFQ 300
  301 IAKGMEYLIH VPCVHRDLAL RNVLIKGNMV IRIADFGLAR RHKNKDYYKT QSVDTPLPIH 360
  361 WMAPESIDKL LFTQKSDVWS YGVCLYELFS LGKSPYKNVI KYDERDSYCK YVLAYLNEGK 420
  421 RLAQPAHADA EIYNVMKLCW DLDMNSRTTF LDCIEFFEKE LKTTSNEYFL DLTRKLRSET 480
  481 NNQLRLSNWL SDEKHCDS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
protein binding	3.13677730481089	bayes_pls_golite062009
binding	3.06905798270146	bayes_pls_golite062009
actin filament binding	2.59742039155224	bayes_pls_golite062009
cytoskeletal protein binding	2.21254869336424	bayes_pls_golite062009
signal transducer activity	1.80011194349017	bayes_pls_golite062009
molecular transducer activity	1.80011194349017	bayes_pls_golite062009
actin binding	1.79651396322487	bayes_pls_golite062009
vinculin binding	1.63216315345235	bayes_pls_golite062009
transporter activity	0.896907103596953	bayes_pls_golite062009
epidermal growth factor receptor binding	0.80673395326897	bayes_pls_golite062009
transmembrane transporter activity	0.713068405985864	bayes_pls_golite062009
substrate-specific transporter activity	0.500685400112742	bayes_pls_golite062009
insulin receptor binding	0.275913005279959	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.272368655500689	bayes_pls_golite062009
receptor binding	0.0742205785215131	bayes_pls_golite062009
ion transmembrane transporter activity	0.00318812576030902	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..148]	PSI-BLAST	19.221849	SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE
2	View Details	[149..498]	PSI-BLAST	82.69897	No description for 2pvfA was found.

Protein Overview: old-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: