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Protein Overview: ppk3

General Information:
Name(s) found: ppk3 / SPAC15A10.13 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • serine/threonine protein kinase Ppk3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDALink to PubMed article]
    Biological Process: signal transduction [RCALink to PubMed article]
    tRNA export from nucleus [ISSLink to PubMed article]
    protein amino acid phosphorylation [IEA]
    Molecular Function: ATP binding [IEA]
    protein kinase activity [IEA]
    protein serine/threonine kinase activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFIKSAASF IAKAGSQFPY DLNEKIPLSS NSVWTLQTGS IRESAQPCSV FSISLSTHPE  60
   61 WAELADRACE TMKTLRHPCI IKYLSTYKSS THLYIATETV RPVTTELNEL SAEIKTYGLW 120
  121 RVSAALSFLN DKNIVHGNLQ MSSVYLNSAD EWIIGDFFLA GDSPQFIKDN HDKILNWSRL 180
  181 VPFEIQSSTL NSASFIYLDS YELGKFISHL YNGTPGDLSQ RGNIPANIFV SAKKLLNVEG 240
  241 KQKLLASEFL KLGERPGGFF RTHLITLYEL LSEVRINEEE DRVKLKQLLS SKLEVIPKNY 300
  301 IQKVVLNILF LLLSIDTHSD VVELLFKCAQ IVKGRPDIEK DFGVPLLSLL KQQSVPIRGL 360
  361 LLSGIINNPD VLPKNIYEDT SFSVFANLVR SNSPTLKEHA IVVFSIIAPK LSKKTLNNEL 420
  421 LRSLAVVQND QHPTLRTNST ICLGKIAEYL DASVRKPVLA AALSRSLKDP FVPAREAALK 480
  481 VLLSVQNYFD TKDVAIKLFP SVVPLLIDEN EGIRRTAEDV TDQFLSRIKN FNLGEKENVS 540
  541 APAKFNGSFW SKFIHSSSAS PSPSIDMKKE SLELKNDTTE IKEKKNSKSR VVGNTENSKD 600
  601 EFNNPLFETE EQIDESWMEN WNDEEETENN VEESWGL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..432] PSI-BLAST 45.09691 G-protein coupled receptor kinase 2, N-terminal domain; G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1); G-protein coupled receptor kinase 2
    2 View Details [433..557] PSI-BLAST 32.522879 Constant regulatory domain of protein phosphatase 2a, pr65alpha
    3 View Details [558..637] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  2.52009208560575 bayes_pls_golite062009
  • binding
    		•  2.26863398810301 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.07522371528074 bayes_pls_golite062009
  • protein kinase activity
    		•  1.05576788307899 bayes_pls_golite062009
  • kinase activity
    		•  1.02766245357265 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.864377119360303 bayes_pls_golite062009
  • Ran GTPase binding
    		•  0.69155782303647 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.611829373978789 bayes_pls_golite062009
  • enzyme binding
    		•  0.42115599703234 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • transferase activity
    		•  0.351512711954014 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.173125467317897 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.0884767565575595 bayes_pls_golite062009
  • transporter activity
    		•  0.0356867444078989 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle