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Protein Overview: pik3

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..801] PSI-BLAST 163.0 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • 1-phosphatidylinositol-3-kinase activity
  • 8.12544462052019 bayes_pls_golite062009
  • phosphoinositide 3-kinase activity
  • 8.10715314025226 bayes_pls_golite062009
  • lipid kinase activity
  • 5.98454599133418 bayes_pls_golite062009
  • inositol or phosphatidylinositol kinase activity
  • 5.59422890717019 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
  • 5.49988294224815 bayes_pls_golite062009
  • kinase activity
  • 5.3287080791198 bayes_pls_golite062009
  • protein kinase activity
  • 5.17195961442593 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 4.96052051118534 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate 3-kinase activity
  • 4.51744163880238 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 4.46381887831481 bayes_pls_golite062009
  • transferase activity
  • 3.97138602499442 bayes_pls_golite062009
  • calcium-dependent phospholipid binding
  • 2.37116581763683 bayes_pls_golite062009
  • protein tyrosine kinase activity
  • 2.36057410204148 bayes_pls_golite062009
  • binding
  • 2.31930216202447 bayes_pls_golite062009
  • profilin binding
  • 2.1052288288978 bayes_pls_golite062009
  • ATP binding
  • 1.97600611746091 bayes_pls_golite062009
  • structural constituent of ribosome
  • 1.97522797979421 bayes_pls_golite062009
  • molecular transducer activity
  • 1.95775692939268 bayes_pls_golite062009
  • signal transducer activity
  • 1.95775692939268 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 1.90928021591891 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
  • 1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
  • 1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
  • 1.63195828048121 bayes_pls_golite062009
  • receptor signaling protein activity
  • 1.63027742934354 bayes_pls_golite062009
  • protein transmembrane transporter activity
  • 1.4515576307774 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
  • 1.38496328649031 bayes_pls_golite062009
  • neurexin binding
  • 1.37902741014529 bayes_pls_golite062009
  • transmembrane receptor activity
  • 1.27941426224024 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
  • 1.27740808551012 bayes_pls_golite062009
  • protein binding
  • 1.22565748038754 bayes_pls_golite062009
  • catalytic activity
  • 1.21655087018101 bayes_pls_golite062009
  • receptor activity
  • 1.13726344123824 bayes_pls_golite062009
  • transporter activity
  • 1.11833481501707 bayes_pls_golite062009
  • transmembrane transporter activity
  • 0.97575992765505 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
  • 0.96468055729151 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
  • 0.58590430118616 bayes_pls_golite062009
  • signal sequence binding
  • 0.57106697498903 bayes_pls_golite062009
  • MAP kinase activity
  • 0.5066845540941 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
  • 0.48345772948903 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 0.451090007290896 bayes_pls_golite062009
  • magnesium ion binding
  • 0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
  • 0.37115026509016 bayes_pls_golite062009
  • clathrin binding
  • 0.35775052108553 bayes_pls_golite062009
  • MAP kinase kinase activity
  • 0.35402045013148 bayes_pls_golite062009
  • protein complex binding
  • 0.265979208658691 bayes_pls_golite062009
  • active transmembrane transporter activity
  • 0.252495966234234 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
  • 0.205652638854091 bayes_pls_golite062009
  • nuclear localization sequence binding
  • 0.200784507667389 bayes_pls_golite062009
  • hydrolase activity
  • 0.056449407710228 bayes_pls_golite062009
  • primary active transmembrane transporter activity
  • 0.00492507437049428 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0040394359628233 bayes_pls_golite062009
  • protein tag
  • 0.00311613478935058 bayes_pls_golite062009




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle