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Protein Overview: prp2

General Information:
Name(s) found: prp2 / SPBC146.07 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • U2AF large subunit (U2AF-59) [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 517 amino acids

    Gene Ontology:
    Cellular Component: commitment complex [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    U2 snRNP [TASLink to PubMed article]
    Biological Process: RNA splicing, via transesterification reactions [ISSLink to PubMed article]
    generation of catalytic spliceosome for first transesterification step [IDALink to PubMed article]
    nuclear mRNA branch site recognition [ISSLink to PubMed article]
    nuclear mRNA splicing, via spliceosome [IMPLink to PubMed article]
    Molecular Function: snoRNA binding [TASLink to PubMed article]
    mRNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLSSRLSSG SSRIPKRHRD YRDEEPRRER GSGGIGREDP RGHYGSERPR RRRRDESDFR  60
   61 RHRESRERSY REDERPRRER RYDDYEPRSL RYSSVGRSRS PPPSRERSVR SIEQELEQLR 120
  121 DVTPINQWKR KRSLWDIKPP GYELVTADQA KMSGVFPLPG APRAAVTDPE KLLEFARSAE 180
  181 GSIIAPPPPL QPGASRQARR LVVTGIPNEF VEDAFVSFIE DLFISTTYHK PETKHFSSVN 240
  241 VCKEENFAIL EVATPEDATF LWGLQSESYS NDVFLKFQRI QNYIVPQITP EVSQKRSDDY 300
  301 AKNDVLDSKD KIYISNLPLN LGEDQVVELL KPFGDLLSFQ LIKNIADGSS KGFCFCEFKN 360
  361 PSDAEVAISG LDGKDTYGNK LHAQFACVGL NQAMIDKSNG MAILTELAKA SSQSIPTRVL 420
  421 QLHNLITGDE IMDVQEYEDI YESVKTQFSN YGPLIDIKIP RSIGTRNSGL GTGKVFVRYS 480
  481 DIRSAEVAME EMKGCKFNDR TIVIAFYGED CYKANAW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] MSA 5.128997 View MSA. No confident structure predictions are available.
    2 View Details [112..192] deduced N/A No confident structure predictions are available.
    3 View Details [193..307] PSI-BLAST 29.522879 Hu antigen D (Hud)
    4 View Details [308..517] PSI-BLAST 29.154902 Poly(A)-binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.92450390013691 bayes_pls_golite062009
  • DNA binding
    		•  1.8021593476478 bayes_pls_golite062009
  • structural molecule activity
    		•  1.29928829870122 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15127506309683 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.425042944899091 bayes_pls_golite062009
  • transporter activity
    		•  0.417047632648771 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.288834004308736 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.288804044686487 bayes_pls_golite062009
  • snoRNA binding
    		•  0.0568636182001701 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00171911393626201 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle