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Protein Overview: CG42251-PD

General Information:
Name(s) found: CG42251-PD / FBpp0288808 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG42251 (CG42251, FBgn0259109). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12413012..12425266. It has the cytological map location 11B1. Based on sequence similarity, it is predicted to have molecular function</span>: SH3/SH2 adaptor activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1416 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: NONE FOUND
    Molecular Function: SH3/SH2 adaptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLSFLFRPF FISVLPAIRT KQLPFGEAQQ ALQLQPAAAA ATAAATTSAA AAANATAAAP  60
   61 QLPPPLPVPV ATLPNQAATA AAAATAAILA THQQQQQQQH QHLSNNNNNG GSTHGQQHTH 120
  121 SNNNNTLPVG AQQQQQQQHQ QQRATLQHPP LPNSNIKQAS VKLIEGYSDP KDTRNHKKVY 180
  181 HKKAKKRSTT GHKRHQQQQQ QQQPHQQQLQ QQQQQTLPTP RSAQQQQQLQ QKLQQRHSTY 240
  241 NNNNGNSRKD KRNSQYNSDS SAPKSSDDEA DIDEEVEQQP LPVPQAPVQS ASQPAAGLNS 300
  301 PDSISDDLVR PLPPQLQRSP RKLTVAPAEH NKRQPSPYYY SDLLKSRDKD KDKDKDKDKD 360
  361 KDKDKDKDKD KDKERDKDRE DFKLKCRQST ASEPPQQTQT QLGGYRKSSS LDVPPAEEQP 420
  421 EAESHEEEDP RTGQDSQSTP KRYSFTEEGV HIIRCETPST STSEESDCSE CLKRREWHAR 480
  481 ALALVRKTCN VQPRNQNPTG SELQLQLQHC DAGEGELLKC CPPPPAPAEN QSQVQPMPPH 540
  541 RLLGPAAVCG ACITSAPASS LAGGRGSELG DDLEEEYFRP RSIFYVHPHG VHECIECAQP 600
  601 AQPATVPAPT LSNPSLDIYG DDEDEVDGDE DEDEEDDSED IMGSRRRQIY ETAFDCKIAK 660
  661 SDDDLDEVDR ITNCSVLLQL SNGNGGDISK VTGSSKTRAE CKRAKNSKNQ ALQEQTGEAH 720
  721 VQVHHVEAEL GKLQLSQVDQ QNQNQNQSQN QQHGVSATGS GASASSTQQL PVRGYTPSPP 780
  781 STAPLPMKFP GKHDRYLNMN SIRSAPNLPA ANPAHPRLRD LRLPIQSMRH QCGGSSNDNS 840
  841 LTDSAYVNPP STNSNSNAAS ASASASVSAT GSAAPRRPRS FVLESGRVLE LRRSAQGHQG 900
  901 GQSTHHHHHH HHHAPGSRRN RHGQSQGQTT GGGHNYSSTE SIATSSSGGS MESLRSSTSE 960
  961 GNRSTSSSES RHSSSLSSHS SESGSGGSGG SGGSSVAYPL RPAPLLLHSK LHILSPISDK1020
 1021 SSQEPASASA SEQSQQPSQQ LAPMASQEDD STTSGAPAGN QVQVNASLKQ PRSNRGAPNK1080
 1081 ALLQLADELL GSDSGISLHS REDGKPQALA LQRLTLPKLQ LIGAEGTTTS ATASGAGGSS1140
 1141 ATGGSSGAGG SGSGSVVASG STGIQQDLRD LPFDMPKLRR RKTLQQEAAC TSGSATSVDL1200
 1201 GELPFDMPKL RRRLRANQAE INNLLMHSTE SSGISQASSS HSMRDDQKMS SKLDTALFRQ1260
 1261 NLTLNLNESR QATKQFGSLD LRGLNSNKEL NMNLSQGYVT AVDLIDVTIP LERQGWYHGA1320
 1321 ITRIEAETTL RPLSEGSFLV RNCESTKQDY SLSLKGAKGF MHMRIQRNET GQYILGQFSR1380
 1381 PFETVPEMIR HFCLNRLPVR GAEHMCLIEP VIAQLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] PSI-BLAST 13.69897 Heavy meromyosin subfragment
    2 View Details [328..581] PSI-BLAST 6.522879 Tropomyosin
    3 View Details [582..801] deduced N/A No confident structure predictions are available.
    4 View Details [802..920] deduced N/A No confident structure predictions are available.
    5 View Details [921..1094] MSA 1.311996 View MSA. No confident structure predictions are available.
    6 View Details [1095..1175] deduced N/A No confident structure predictions are available.
    7 View Details [1176..1416] PSI-BLAST 45.045757 No description for 2h8hA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • binding
    		•  0.434026084000615 bayes_pls_golite062009
  • protein binding
    		•  0.31534665043077 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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