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Protein Overview: raps-PA

General Information:
Name(s) found: raps-PA / FBpp0084559 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene rapsynoid is referred to in FlyBase by the symbol Dmel\raps (CG5692, FBgn0040080). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23408527..23412098. It has the cytological map location 98A8. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment of mitotic spindle orientation; neuroblast proliferation; asymmetric neuroblast division; establishment of spindle orientation; asymmetric cell division. 18 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; RP2 neuron; neuroblast; ganglion mother cell GMC4-2a; intersegmental nerve; centrosome; spindle; RP2sib neuron; larval neuroblast; aster. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 658 amino acids

    Gene Ontology:
    Cellular Component: apical part of cell [NAS]
    cell cortex [TAS]
    apical cortex [IDA][TAS]
    Biological Process: establishment of mitotic spindle orientation [IMP]
    maintenance of protein location [NAS]
    neuroblast proliferation [IMP]
    establishment of mitotic spindle localization [TAS]
    asymmetric protein localization involved in cell fate determination [TAS]
    signal transduction [IEA]
    basal protein localization [TAS]
    asymmetric cell division [IMP][NAS][TAS]
    neuroblast fate determination [TAS]
    establishment of spindle orientation [IMP]
    asymmetric neuroblast division [IMP]
    asymmetric protein localization [TAS]
    Molecular Function: protein binding [IPI]
    GTPase activator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSASAEN VSSLGLGSGG GGTTSHDGNS QQGSGSDGGS SMCLELALEG ERLCKAGDCR  60
   61 AGVAFFQAAI QAGTEDLRTL SAIYSQLGNA YFYLGDYNKA MQYHKHDLTL AKSMNDRLGE 120
  121 AKSSGNLGNT LKVMGRFDEA AICCERHLTL ARQLGDRLSE GRALYNLGNV YHAKGKHLGQ 180
  181 RNPGKFGDDV KEALTRAVEF YQENLKLMRD LGDRGAQGRA CGNLGNTYYL LGDFQAAIEH 240
  241 HQERLRIARE FGDRAAERRA NSNLGNSHIF LGQFEDAAEH YKRTLALAVE LGEREVEAQS 300
  301 CYSLGNTYTL LHEFNTAIEY HNRHLAIAQE LGDRIGEARA CWSLGNAHSA IGGHERALKY 360
  361 AEQHLQLAKE LHDPVGESTA RVNISDLRKL LGMPDSEPSP TEEEARSTAS DHSASGNQSD 420
  421 GSENSQGRMV RVRRQSMEQL DLIKITPDGK RMQEEKLRAQ ATRKAKDDDF FEMLSRSQSK 480
  481 RMDDQRCSIK VNPAGAPAVA TGATRKPLVQ QNSLFVDPTN LPGLKSPSSA NPSAIGHGPL 540
  541 ARSATTTQQP DDDFLDMLMR CQGSRLEEQR SELPRPNVTM DAEAEAPPRS VPEAAVPGAP 600
  601 RGQTGRGATV PDEDFFSLIM KVQSGRMEDQ RASIPFRNAN NNNNSRSNNN GSAGGAGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..290] PSI-BLAST 6.39794 Helicobacter cysteine rich protein C (HcpC)
    2 View Details [291..351] FFAS03 2.5 No description for 2ifuA was found.
    3 View Details [352..584] PSI-BLAST 5.69897 Crystal structure of E.coli TPR-protein NlpI
    4 View Details [585..658] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.32969330984971 bayes_pls_golite062009
  • protein binding
    		•  0.559882636047776 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.07985546140154 bayes_pls_golite062009
  • protein binding
    		•  1.6279032205159 bayes_pls_golite062009
  • signal sequence binding
    		•  0.84653836601323 bayes_pls_golite062009
  • peptide binding
    		•  0.646032841722384 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle