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The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Process by which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus. Process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast. The process whereby a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: neuroblast fate determination
Acc: GO:0007400
Aspect: Biological Process
Desc: Process by which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.
Synonyms:
  • GO:0007408
  • neuroblast identity determination
  • neuroblast cell fate determination
  • GO:0043347
  • GO:0043348
Proteins in PDR annotated with:
   This term: 39 [Search]
   Term or descendants: 39 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007400 - neuroblast fate determination (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle