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Protein Overview: CG8412-PA

General Information:
Name(s) found: CG8412-PA / FBpp0081608 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8412 (CG8412, FBgn0037743). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5582215..5585035. It has the cytological map location 85E6. Based on sequence similarity, it is predicted to have molecular function</span>: alpha-1,6-mannosyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: dolichol-linked oligosaccharide biosynthetic process; protein amino acid glycosylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 678 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [ISS]
    intrinsic to endoplasmic reticulum membrane [IEA]
    Biological Process: GPI anchor biosynthetic process [IEA]
    protein amino acid glycosylation [ISS]
    dolichol-linked oligosaccharide biosynthetic process [ISS]
    Molecular Function: alpha-1,6-mannosyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDILIFVTAA AHLVYTPFTK VEESFNLQAM HDILYLRNNF TQYDHHDYPG VVPRTFIGPL  60
   61 VVSIISAPFV LLFETLSINK FWAQYVVRLV LAGAISVAWN SLRQAVTKIY GVEVRLWFTA 120
  121 ITITQFHFMF YMTRPLPNIF ALPIVLFAIA YWLRDQHKPF IICSGISILV FRSELALFLG 180
  181 ILLVVSLLRR KVSIDGLLKV ALPAGVCILA ATVLVDSFFW RRLLWPEGEV LWYNTVLNKS 240
  241 SNWGTSPFLW YFYSALPRAM GASLVLVPIG VALEPRIRPL VLSALLFVLL YSILPHKELR 300
  301 FIIYVFPVLN IAAACACQRI WMNSAKSTWH SFLALACGAH LLLNVFITLF LLVISGTNYP 360
  361 GGAALSRLHR LEAGTSNVSV HISNLAAQSG VSRFMEINNE WTYSKDETMN YTQADLVAYT 420
  421 HLLVEAKNKQ NTELWASLQN EFDTLEFIDC FNSIGIQYNS LLPVRIKTKP CIGILKKRPV 480
  481 APKEASKTKE KIAKTKTYPV EKETLLAPVK EFPKVIGDPK MKSRLQVDAD DDDGIVSTVE 540
  541 EMSLELETDT EPHAGAETIE TPLKEINFQE LRTLALGQAT KKSRAATKMK IRQIIEQHYR 600
  601 AKGKQIENDS AETQKTQGKA GLRQSVKSII KQEKIKEMIE QIATMDLTRI CDLERTSTKD 660
  661 CLKQVIDKID DSEGLKSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] deduced N/A No confident structure predictions are available.
    2 View Details [78..446] PSI-BLAST 4.154902 Cytochrome O ubiquinol oxidase, subunit I
    3 View Details [447..678] PSI-BLAST 16.154902 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.95966890211023 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  0.761287090069338 bayes_pls_golite062009
  • binding
    		•  0.733970829597091 bayes_pls_golite062009
  • cytochrome-c oxidase activity
    		•  0.35515397335228 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  0.35515397335228 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  0.35515397335228 bayes_pls_golite062009
  • protein binding
    		•  0.318971252142179 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.0678092463846129 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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