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View Structure Prediction Details

Protein: CG8412-PA
Organism: Drosophila melanogaster
Length: 678 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8412-PA.

Description E-value Query
Range
Subject
Range
gi|54638331, gi|... - gi|54638331|gb|EAL27733.1| GA21058-PA [Drosophila pseudoobscura], gi|125774667|ref|XP_001358592.1| G...
370.0 [0..4] [678..4]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDILIFVTAA AHLVYTPFTK VEESFNLQAM HDILYLRNNF TQYDHHDYPG VVPRTFIGPL  60
   61 VVSIISAPFV LLFETLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [78-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INKFWAQYVV RLVLAGAISV AWNSLRQAVT KIYGVEVRLW FTAITITQFH FMFYMTRPLP  60
   61 NIFALPIVLF AIAYWLRDQH KPFIICSGIS ILVFRSELAL FLGILLVVSL LRRKVSIDGL 120
  121 LKVALPAGVC ILAATVLVDS FFWRRLLWPE GEVLWYNTVL NKSSNWGTSP FLWYFYSALP 180
  181 RAMGASLVLV PIGVALEPRI RPLVLSALLF VLLYSILPHK ELRFIIYVFP VLNIAAACAC 240
  241 QRIWMNSAKS TWHSFLALAC GAHLLLNVFI TLFLLVISGT NYPGGAALSR LHRLEAGTSN 300
  301 VSVHISNLAA QSGVSRFMEI NNEWTYSKDE TMNYTQADLV AYTHLLVEAK NKQNTELWAS 360
  361 LQNEFDTLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1fftA
Description: Cytochrome O ubiquinol oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.95966890211023 bayes_pls_golite062009
heme-copper terminal oxidase activity 0.761287090069338 bayes_pls_golite062009
binding 0.733970829597091 bayes_pls_golite062009
cytochrome-c oxidase activity 0.35515397335228 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 0.35515397335228 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.35515397335228 bayes_pls_golite062009
protein binding 0.318971252142179 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.0678092463846129 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [447-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIDCFNSIGI QYNSLLPVRI KTKPCIGILK KRPVAPKEAS KTKEKIAKTK TYPVEKETLL  60
   61 APVKEFPKVI GDPKMKSRLQ VDADDDDGIV STVEEMSLEL ETDTEPHAGA ETIETPLKEI 120
  121 NFQELRTLAL GQATKKSRAA TKMKIRQIIE QHYRAKGKQI ENDSAETQKT QGKAGLRQSV 180
  181 KSIIKQEKIK EMIEQIATMD LTRICDLERT STKDCLKQVI DKIDDSEGLK SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle