Protein Overview: Ptp69D-PA

General Information:
Name(s) found:	Ptp69D-PA / FBpp0075645 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|73920745\|sp\|P16620.2\|PTP69_DROME RecName: Full=Tyrosine-protein phosphatase 69D; AltName: Full=Protein-tyrosine-phosphate phosphohydrolase; Short=DPTP; Flags: Precursor [NCBI NR] gi\|24663403\|ref\|NP_524048.2\| protein tyrosine phosphatase 69D, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093573\|gb\|AAF49892.2\| protein tyrosine phosphatase 69D, isoform A [Drosophila melanogaster] [NCBI NR] Tyrosine-protein phosphatase 69D OS=Drosophila melanogaster GN=Ptp69D PE=1 SV=2 [Swiss-Prot] The gene Protein tyrosine phosphatase 69D is referred to in FlyBase by the symbol Dmel\Ptp69D (CG10975, FBgn0014007). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12728049..12734668. It has the cytological map location 69D6-69E1. There is experimental evidence that it has the molecular function</span>: protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; protein amino acid dephosphorylation; dendrite morphogenesis; defasciculation of motor neuron axon; axonogenesis. 57 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: embryonic neuron; multi-cell-component structure; embryonic nervous system; nervous system; adult segment; cell projection; neuron projection; organ system; peripheral nervous system; anatomical structure. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG10975-PA translation from_gene[CG10975 Ptp69D FBgn0014007] seq_release:3 mol_weight=167462 cds_boundaries:(3L:12,692,700..12,698,541[+]) aa_length:1462 transcript_info:[CG10975-RA seq_release:3] gene_info:[gene symbol:Ptp69D FBgn0014007 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta] (Q9VU03) CG10975 protein [DrosMelano7227.FASTAC.txt] CG10975-PA, isoform A [Drosophila melanogaster]gi\|24663403\|ref\|NP_524048.2\| CG10975-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(12728253..12728349,12729158..12729260,12729353..12731196,12731256..12731501,12731560..12731803,12731872..12732766,12732826..12732972,12733029..12733139,12733209..12733388,12733453..12733760,12733822..12733957,12734020..12734097); [fly-100309-contam.fasta] Protein tyrosine phosphatase 69D CG10975-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Tyrosine-protein phosphatase 69D precursor (Protein-tyrosine-phosphate phosphohydrolase) (DPTP) [nr-271106-contam.fasta] CG10975-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(12728253..12728349,12729158..12729260,12729353..12731196,12731256..12731501,12731560..12731803,12731872..12732766,12732826..12732972,12733029..12733139,12733209..12733388,12733453..12733760,12733822..12733957,12734020..12734097); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(12728253..12728349,12729158..12729260,12729353..12731196,12731256..12731501,12731560..12731803,12731872..12732766,12732826..12732972,12733029..12733139,12733209..12733388,12733453..12733760,12733822..12733957,12734020..12734097); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(12728253..12728349,12729158..12729260,12729353..12731196,12731256..12731501,12731560..12731803,12731872..12732766,12732826..12732972,12733029..12733139,12733209..12733388,12733453..12733760,12733822..12733957,12734020..12734097); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892,FlyMine:FBpp0075645,modMine:FBpp0075645; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(12735153..12735249,12736058..12736160,12736253..12738096,12738156..12738401,12738460..12738703,12738772..12739666,12739726..12739872,12739929..12740039,12740109..12740288,12740353..12740660,12740722..12740857,12740920..12740997); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892,FlyMine:FBpp0075645,modMine:FBpp0075645; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(12735153..12735249,12736058..12736160,12736253..12738096,12738156..12738401,12738460..12738703,12738772..12739666,12739726..12739872,12739929..12740039,12740109..12740288,12740353..12740660,12740722..12740857,12740920..12740997); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892,FlyMine:FBpp0075645,modMine:FBpp0075645; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0075645 type=protein; loc=3L:join(12735153..12735249,12736058..12736160,12736253..12738096,12738156..12738401,12738460..12738703,12738772..12739666,12739726..12739872,12739929..12740039,12740109..12740288,12740353..12740660,12740722..12740857,12740920..12740997); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892,FlyMine:FBpp0075645,modMine:FBpp0075645; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(12735153..12735249,12736058..12736160,12736253..12738096,12738156..12738401,12738460..12738703,12738772..12739666,12739726..12739872,12739929..12740039,12740109..12740288,12740353..12740660,12740722..12740857,12740920..12740997); ID=FBpp0075645; name=Ptp69D-PA; parent=FBgn0014007,FBtr0075913; dbxref=FlyBase:FBpp0075645,FlyBase_Annotation_IDs:CG10975-PA,GB_protein:AAF49892.2,REFSEQ:NP_524048,GB_protein:AAF49892,UniProt/Swiss-Prot:P16620,FlyMine:FBpp0075645,modMine:FBpp0075645; MD5=b412ac30469b470960b086339632d74e; length=1462; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1462 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [ISS][NAS] axon [IDA]
Biological Process:	motor axon guidance [IGI][IMP] axonogenesis [IMP] protein amino acid dephosphorylation [IDA][NAS] axon guidance [NAS] axonal defasciculation [TAS] defasciculation of motor neuron axon [IGI][IMP] dendrite morphogenesis [IMP]
Molecular Function:	protein tyrosine phosphatase activity [IDA][NAS] receptor signaling protein tyrosine phosphatase activity [NAS] transmembrane receptor protein tyrosine phosphatase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLYRRMSM LLNIILAYIF LCAICVQGSV KQEWAEIGKN VSLECASENE AVAWKLGNQT  60
   61 INKNHTRYKI RTEPLKSNDD GSENNDSQDF IKYKNVLALL DVNIKDSGNY TCTAQTGQNH 120
  121 STEFQVRPYL PSKVLQSTPD RIKRKIKQDV MLYCLIEMYP QNETTNRNLK WLKDGSQFEF 180
  181 LDTFSSISKL NDTHLNFTLE FTEVYKKENG TYKCTVFDDT GLEITSKEIT LFVMEVPQVS 240
  241 IDFAKAVGAN KIYLNWTVND GNDPIQKFFI TLQEAGTPTF TYHKDFINGS HTSYILDHFK 300
  301 PNTTYFLRIV GKNSIGNGQP TQYPQGITTL SYDPIFIPKV ETTGSTASTI TIGWNPPPPD 360
  361 LIDYIQYYEL IVSESGEVPK VIEEAIYQQN SRNLPYMFDK LKTATDYEFR VRACSDLTKT 420
  421 CGPWSENVNG TTMDGVATKP TNLSIQCHHD NVTRGNSIAI NWDVPKTPNG KVVSYLIHLL 480
  481 GNPMSTVDRE MWGPKIRRID EPHHKTLYES VSPNTNYTVT VSAITRHKKN GEPATGSCLM 540
  541 PVSTPDAIGR TMWSKVNLDS KYVLKLYLPK ISERNGPICC YRLYLVRINN DNKELPDPEK 600
  601 LNIATYQEVH SDNVTRSSAY IAEMISSKYF RPEIFLGDEK RFSENNDIIR DNDEICRKCL 660
  661 EGTPFLRKPE IIHIPPQGSL SNSDSELPIL SEKDNLIKGA NLTEHALKIL ESKLRDKRNA 720
  721 VTSDENPILS AVNPNVPLHD SSRDVFDGEI DINSNYTGFL EIIVRDRNNA LMAYSKYFDI 780
  781 ITPATEAEPI QSLNNMDYYL SIGVKAGAVL LGVILVFIVL WVFHHKKTKN ELQGEDTLTL 840
  841 RDSLSRALFG RRNHNHSHFI TSGNHKGFDA GPIHRLDLEN AYKNRHKDTD YGFLREYEML 900
  901 PNRFSDRTTK NSDLKENACK NRYPDIKAYD QTRVKLAVIN GLQTTDYINA NFVIGYKERK 960
  961 KFICAQGPME STIDDFWRMI WEQHLEIIVM LTNLEEYNKA KCAKYWPEKV FDTKQFGDIL1020
 1021 VKFAQERKTG DYIERTLNVS KNKANVGEEE DRRQITQYHY LTWKDFMAPE HPHGIIKFIR1080
 1081 QINSVYSLQR GPILVHCSAG VGRTGTLVAL DSLIQQLEEE DSVSIYNTVC DLRHQRNFLV1140
 1141 QSLKQYIFLY RALLDTGTFG NTDICIDTMA SAIESLKRKP NEGKCKLEVE FEKLLATADE1200
 1201 ISKSCSVGEN EENNMKNRSQ EIIPYDRNRV ILTPLPMREN STYINASFIE GYDNSETFII1260
 1261 AQDPLENTIG DFWRMISEQS VTTLVMISEI GDGPRKCPRY WADDEVQYDH ILVKYVHSES1320
 1321 CPYYTRREFY VTNCKIDDTL KVTQFQYNGW PTVDGEVPEV CRGIIELVDQ AYNHYKNNKN1380
 1381 SGCRSPLTVH CSLGTDRSSI FVAMCILVQH LRLEKCVDIC ATTRKLRSQR TGLINSYAQY1440
 1441 EFLHRAIINY SDLHHIAEST LD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Ptp69D-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: