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Protein Overview: Ote-PA

General Information:
Name(s) found: Ote-PA / FBpp0085947 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Otefin is referred to in FlyBase by the symbol Dmel\Ote (CG5581, FBgn0003022). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14163112..14164698. It has the cytological map location 55C2. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: nuclear envelope reassembly. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: nuclear inner membrane [IDA][NAS]
    nuclear membrane [IDA]
    Biological Process: positive regulation of BMP signaling pathway [IGI]
    female germ-line stem cell division [IMP]
    negative regulation of gene-specific transcription [IMP]
    germ-line stem cell maintenance [IMP]
    nuclear envelope reassembly [IDA]
    Molecular Function: protein binding [IPI]
    transcription corepressor activity [IMP]
    transcription factor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVDDFDSL SNAELRAKML AQGLPNIPVT DSSRKVLVKR LRASIGGQAS PAASPKKTNR  60
   61 RETLAPAPGA PSAPAAASTP VDKLDGNKVA PATKARRTIT AAEAKEPVRR LPEEAIRRRP 120
  121 DEADRLRSEE PVAARKPTTA PAAQPVQTRR TSTSSGSERK VVEPLRKPET IVEQPASSKR 180
  181 ADREENYLKV NSLIVLESDE EEDEQLVQAA DLVEQEHAAR QKTTKLASSG TTTYEYKSKV 240
  241 VEPPRRQVYE ATAAPVLPPS VPSARAQTTS STRSYDYASN PAPGRYSSFV RTAAQGYVTA 300
  301 EAPPVASYSS SYKRTYANEL SDDTDSKEDQ YESTFARNLA RLRAERIGDR ISPYSRRTLA 360
  361 SGNAGSGSLG YEPRARRSLR PNDNSVSEAF NRWLNSLEQK YHIKSKLFIV LLVLLLIGVY 420
  421 YIFY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..66] FFAS03 2.01 Inner nuclear membrane protein emerin
    2 View Details [67..253] MSA 3.158996 View MSA. No confident structure predictions are available.
    3 View Details [254..424] MSA 8.154997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lamin binding
    		•  3.77197010620371 bayes_pls_golite062009
  • binding
    		•  2.42312572249097 bayes_pls_golite062009
  • protein binding
    		•  1.36005487353381 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle