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Protein Overview: tsu-PA

General Information:
Name(s) found: tsu-PA / FBpp0087648 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene tsunagi is referred to in FlyBase by the symbol Dmel\tsu (CG8781, FBgn0033378). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4998306..4999087. It has the cytological map location 45A7. There is experimental evidence that it has the molecular function</span>: SUMO binding. There is experimental evidence that it is involved in the biological process</span>: oocyte anterior/posterior axis specification; oocyte nucleus migration during oocyte axis specification; regulation of pole plasm oskar mRNA localization; microtubule cytoskeleton organization; oocyte dorsal/ventral axis specification. 14 alleles are reported. The phenotypes of these alleles are annotated with: egg; egg chamber; oocyte nucleus; dorsal appendage. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 165 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    catalytic step 2 spliceosome [IDA]
    cytoplasm [IDA]
    Biological Process: mRNA export from nucleus [NAS]
    regulation of pole plasm oskar mRNA localization [IMP][IPI]
    establishment of pole plasm mRNA localization [TAS]
    pole plasm oskar mRNA localization [TAS]
    oocyte nucleus migration during oocyte axis specification [IMP]
    RNA processing [IEA]
    oocyte dorsal/ventral axis specification [IMP]
    microtubule cytoskeleton organization [IMP]
    oocyte anterior/posterior axis specification [IMP]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: nucleotide binding [IEA]
    SUMO binding [IPI]
    mRNA binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVLDIDNA EEFEVDEDGD QGIVRLKEKA KHRKGRGFGS DSNTREAIHS YERVRNEDDD  60
   61 ELEPGPQRSV EGWILFVTSI HEEAQEDEIQ EKFCDYGEIK NIHLNLDRRT GFSKGYALVE 120
  121 YETHKQALAA KEALNGAEIM GQTIQVDWCF VKGPKRVKKS EKRRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..165] PSI-BLAST 30.39794 CG8781 protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  5.15097136329571 bayes_pls_golite062009
  • mRNA binding
    		•  4.05281507540116 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.81920018903278 bayes_pls_golite062009
    		• 3.6767428476083 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.69629099229571 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07788694919471 bayes_pls_golite062009
  • snRNA binding
    		•  1.06008352183728 bayes_pls_golite062009
  • DNA binding
    		•  0.978604858165557 bayes_pls_golite062009
  • transporter activity
    		•  0.628672636801176 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.505106991526286 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.288834004308736 bayes_pls_golite062009
  • transcription factor activity
    		•  0.234742017105535 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.182749906784328 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.096231856558874 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.059732432409948 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0510390778764699 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0484248928275733 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle