YRC Public Data Repository - Protein Structure Prediction

Protein:	tsu-PA
Organism:	Drosophila melanogaster
Length:	165 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tsu-PA.

Description	E-value	Query Range	Subject Range
gi\|73974162 - gi\|73974162\|ref\|XP_857372.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	157.0	[0..3]	[162..21]
gi\|109491620 - gi\|109491620\|ref\|XP_001081205.1\| PREDICTED: similar to Musashi homolog 2 [Rattus norvegicus]	157.0	[0..2]	[165..192]
gi\|70989777, gi\|... - gi\|70989777\|ref\|XP_749738.1\| heterogeneous nuclear ribonucleoprotein HRP1 [Aspergillus fumigatus Af2...	156.0	[0..3]	[154..115]
gi\|32822918, gi\|... - gi\|41056104\|ref\|NP_957403.1\| musashi homolog 2 [Danio rerio], gi\|32822918\|gb\|AAH55251.1\| Musashi hom...	155.0	[0..7]	[165..35]
gi\|116197887, gi... - gi\|88178378\|gb\|EAQ85846.1\| hypothetical protein CHGG_07099 [Chaetomium globosum CBS 148.51], gi\|1161...	153.0	[0..3]	[164..399]
gi\|94373120 - gi\|94373120\|ref\|XP_982196.1\| PREDICTED: similar to heterogeneous nuclear ribonucleoprotein A3 [Mus m...	153.0	[0..3]	[157..45]
gi\|124358513, gi... - gi\|125630689\|ref\|NP_001074996.1\| musashi 1 [Bos taurus], gi\|124358513\|dbj\|BAF45938.1\| RNA-binding pr... HGNC:7330\|MIM:60... - homolog 1 (Drosophila) gi\|208966796, gi... - gi\|208966796\|dbj\|BAG73412.1\| musashi homolog 1 [synthetic construct], gi\|148921740\|gb\|AAI46464.1\| Mu... MSI1 - musashi homolog 1 (Drosophila)	152.0	[0..4]	[164..31]
gi\|76610797 - gi\|76610797\|ref\|XP_605827.2\| PREDICTED: similar to musashi 1 [Bos taurus]	151.0	[0..4]	[164..10]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVLDIDNA EEFEVDEDGD QGIVRLKEKA KHRKGRGFGS DSNTREAIHS YERVRNEDDD  60
   61 ELEPGPQRSV EGWILFVTSI HEEAQEDEIQ EKFCDYGEIK NIHLNLDRRT GFSKGYALVE 120
  121 YETHKQALAA KEALNGAEIM GQTIQVDWCF VKGPKRVKKS EKRRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.39794
Match:	1hl6A
Description:	CG8781 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	5.15097136329571	bayes_pls_golite062009
mRNA binding	4.05281507540116	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
	3.6767428476083	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
poly-pyrimidine tract binding	1.69629099229571	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
snRNA binding	1.06008352183728	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
transporter activity	0.628672636801176	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
transmembrane transporter activity	0.505106991526286	bayes_pls_golite062009
cytoskeletal protein binding	0.288834004308736	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009
substrate-specific transporter activity	0.182749906784328	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.096231856558874	bayes_pls_golite062009
pyrophosphatase activity	0.059732432409948	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0510390778764699	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0484248928275733	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: