Protein Overview: FBpp0308004, cac...

General Information:
Name(s) found:	FBpp0308004 [FlyBase] cact-PD / FBpp0089296 [FlyBase] cact-PB / FBpp0080403 [FlyBase] cact-PA / FBpp0080402 [FlyBase]
Description(s) found: Found 57 descriptions. SHOW ALL	type=protein; loc=2L:complement(16313379..16313450,16314451..16314708,16314770..16314858,16322960..16323170,16323340..16323517,16324333..16325027); ID=FBpp0308004; name=cact-PE; parent=FBgn0000250,FBtr0337081; dbxref=REFSEQ:NP_001260496,GB_protein:AGB93031,FlyBase:FBpp0308004,FlyBase_Annotation_IDs:CG5848-PE; MD5=a0196cd955e2b5da81cbb10160084e2b; length=500; release=r5.56; species=Dmel; [FlyBase] The gene cactus is referred to in FlyBase by the symbol Dmel\cact (CG5848, FBgn0000250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16313029..16326101. It has the cytological map location 35F1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: antifungal humoral response; nervous system development; dorsal/ventral axis specification; oogenesis; antimicrobial humoral response; positive regulation of antifungal peptide biosynthetic process; cellular response to DNA damage stimulus; dorsal appendage formation; phagocytosis, engulfment. 126 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval hemocoel; anatomical structure; portion of tissue; integumentary system; hemocyte; cuticle; egg; podocyte; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene cactus is referred to in FlyBase by the symbol Dmel\cact (CG5848, FBgn0000250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16313029..16326101. It has the cytological map location 35F1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: antifungal humoral response; nervous system development; dorsal/ventral axis specification; oogenesis; antimicrobial humoral response; positive regulation of antifungal peptide biosynthetic process; cellular response to DNA damage stimulus; dorsal appendage formation; phagocytosis, engulfment. 126 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval hemocoel; anatomical structure; portion of tissue; integumentary system; hemocyte; cuticle; egg; podocyte; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene cactus is referred to in FlyBase by the symbol Dmel\cact (CG5848, FBgn0000250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16313029..16326101. It has the cytological map location 35F1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: antifungal humoral response; nervous system development; dorsal/ventral axis specification; oogenesis; antimicrobial humoral response; positive regulation of antifungal peptide biosynthetic process; cellular response to DNA damage stimulus; dorsal appendage formation; phagocytosis, engulfment. 126 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval hemocoel; anatomical structure; portion of tissue; integumentary system; hemocyte; cuticle; egg; podocyte; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	500 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA][NAS][TAS] neuromuscular junction [IDA]
Biological Process:	Toll signaling pathway [NAS][TAS] negative regulation of protein import into nucleus [NAS] hemopoiesis [TAS] nervous system development [IMP] dorsal appendage formation [IMP] dorsal/ventral axis specification [IMP][TAS] response to fungus [TAS] cytoplasmic sequestering of transcription factor [ISS] defense response [NAS][TAS] response to DNA damage stimulus [IMP] positive regulation of antifungal peptide biosynthetic process [IMP] immune response [TAS] phagocytosis, engulfment [IMP] oogenesis [IMP] innate immune response [NAS] antimicrobial humoral response [IEP] antifungal humoral response [IMP]
Molecular Function:	protein binding [IPI] transcription factor binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSPTKAAEA ATKATATSDC SCSAASVEQR APSNAANPSS SLATSGKIGG KTQDQTAAIN  60
   61 KQKEFAVPNE TSDSGFISGP QSSQIFSEEI VPDSEEQDKD QQESAPQKEQ PVVLDSGIID 120
  121 EEEDQEEQEK EEEHQDTTTA TADSMRLKHS ADTGIPQWTV ESHLVSRGEQ LNNLGQSSST 180
  181 QITGRSKVQS STASTANANP SGSGATSSAP PSSINIMNAW EQFYQQNDDG DTPLHLACIS 240
  241 GSVDVVAALI RMAPHPCLLN IQNDVAQTPL HLAALTAQPN IMRILLLAGA EPTVRDRHGN 300
  301 TALHLSCIAG EKQCVRALTE KFGATEIHEA HRQYGHRSND KAVSSLSYAC LPADLEIRNY 360
  361 DGERCVHLAA EAGHIDILRI LVSHGADINA REGKSGRTPL HIAIEGCNED LANFLLDECE 420
  421 KLNLETATYA GLTAYQFACI MNKSRMQNIL EKRGAETVTP PDSDYDSSDI EDLDDTKMYD 480
  481 RFGDPRYFVS YNGGNPMTVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.78

Protein Overview: FBpp0308004, cac...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: