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The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell. The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. Any process by which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. The directed movement of a transcription factor from the cytoplasm to the nucleus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cytoplasmic sequestering of transcription factor
Acc: GO:0042994
Aspect: Biological Process
Desc: The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:
  • transcription factor binding, cytoplasmic sequestering
  • sequestering of transcription factor in cytoplasm
  • sequestration of transcription factor in cytoplasm
  • retention of transcription factor in cytoplasm
  • cytoplasmic storage of transcription factor
  • maintenance of transcription factor protein location in cytoplasm
  • cytoplasmic retention of transcription factor
  • cytoplasmic sequestration of transcription factor
  • storage of transcription factor in cytoplasm
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042994 - cytoplasmic sequestering of transcription factor (interactive image map)
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