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Protein Overview: FSHB_RAT

General Information:
Name(s) found: FSHB_RAT [Swiss-Prot]
Description(s) found:
Found 25 descriptions.
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  • Follitropin subunit beta OS=Rattus norvegicus GN=Fshb PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 130 amino acids

    Gene Ontology:
    Cellular Component: follicle-stimulating hormone complex [TAS]
    extracellular region [UNKNOWN][IEA]
    Biological Process: Sertoli cell proliferation [UNKNOWN][IEA]
    transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA]
    follicle-stimulating hormone signaling pathway [TAS]
    Molecular Function: follicle-stimulating hormone activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKSIQLCIL LWCLRAVCCH SCELTNITIS VEKEECRFCI SINTTWCEGY CYTRDLVYKD  60
   61 PARPNTQKVC TFKELVYETI RLPGCARHSD SLYTYPVATE CHCGKCDSDS TDCTVRGLGP 120
  121 SYCSFGEMKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] PSI-BLAST 40.69897 Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  4.98600168355158 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
    		•  4.8369569327215 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  4.69128752159226 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  4.69128752159226 bayes_pls_golite062009
  • growth factor activity
    		•  4.01406832911234 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 1 binding
    		•  3.35517597922994 bayes_pls_golite062009
  • cytokine activity
    		•  2.90799896011039 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  2.76400237542695 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
    		•  2.7562170740679 bayes_pls_golite062009
  • binding
    		•  2.64101807129423 bayes_pls_golite062009
  • growth factor binding
    		•  2.41942870726502 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 2 binding
    		•  2.36823915226245 bayes_pls_golite062009
  • protein binding
    		•  2.36794464190805 bayes_pls_golite062009
  • cell surface binding
    		•  2.33284053060339 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.9734035688309 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  1.78479767888975 bayes_pls_golite062009
  • heparin binding
    		•  1.73353807509439 bayes_pls_golite062009
  • pattern binding
    		•  1.34327634476459 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.17302952845956 bayes_pls_golite062009
  • platelet-derived growth factor binding
    		•  1.16893591942376 bayes_pls_golite062009
  • hormone activity
    		•  0.94314407550729 bayes_pls_golite062009
  • SMAD binding
    		•  0.918765103972039 bayes_pls_golite062009
  • collagen binding
    		•  0.894753581887191 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.697058311884552 bayes_pls_golite062009
  • follicle-stimulating hormone activity
    		•  0.648906125812902 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.37618196282327 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.344090347736442 bayes_pls_golite062009
  • identical protein binding
    		•  0.273591586673912 bayes_pls_golite062009
  • fibronectin binding
    		•  0.1110090445978 bayes_pls_golite062009
  • catalytic activity
    		•  0.105223830172599 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 3 binding
    		•  0.0796166411998893 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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