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The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands, contributing to the formation of the neural plate anterior/posterior pattern. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to the specification of the oral/aboral axis. The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands contributing to the formation of the primitive streak. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to the process of heart jogging. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt a mesoderm fate. The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to determination of organismal asymmetry with respect to the left and right halves. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase. Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transforming growth factor beta receptor signaling pathway
Acc: GO:0007179
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.
Synonyms:
  • TGF-beta receptor signalling pathway
  • TGFbeta receptor signaling pathway
  • TGF-beta receptor signaling pathway
  • transforming growth factor beta receptor signalling pathway
  • TGFbeta receptor signalling pathway
Proteins in PDR annotated with:
   This term: 193 [Search]
   Term or descendants: 283 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007179 - transforming growth factor beta receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle