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Protein Overview: gi|108811848, gi...

General Information:
Name(s) found: gi|229902151 [NCBI NR]
gi|229681047 [NCBI NR]
gi|108811848 [NCBI NR]
gi|108775496 [NCBI NR]
Description(s) found:
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  • gi|229902151|ref|ZP_04517272.1| DNA topoisomerase I, omega subunit [Yersinia pestis Nepal516] [NCBI NR]
  • gi|229681047|gb|EEO77142.1| DNA topoisomerase I, omega subunit [Yersinia pestis Nepal516] [NCBI NR]
  • gi|108811848|ref|YP_647615.1| DNA topoisomerase I [Yersinia pestis Nepal516] [NCBI NR]
  • gi|108775496|gb|ABG18015.1| DNA topoisomerase I [Yersinia pestis Nepal516] [NCBI NR]
  • DNA topoisomerase I [Yersinia pestis Nepal516] [nr-271106-contam.fasta]
    • Organism: Yersinia pestis Nepal516
    Length: 871 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKALVIVES PAKAKTINKY LGNDYVVKSS VGHIRDLPTS GSASKKSANS AEEKAKKDDK  60
   61 PKKKVKKDEK VALVNRMGVD PYHGWKAQYE ILSGKEKVVA ELKALAENAD HIYLATDLDR 120
  121 EGEAIAWHLR EVIGGDDKRF SRVVFNEITK NAIQQAFNQP GELNISRVNA QQARRFMDRV 180
  181 VGYMVSPLLW KKIARGLSAG RVQSVAVRLV VEREKEIKAF VPEEYWELHA DLVAKGDIPI 240
  241 QMEVTHAHGK PFKPVNREQT HAALTLLENA RYKVLDREDK PTSSKPSAPF ITSTLQQAAS 300
  301 TRLSFGVKKT MMMAQRLYEA GHITYMRTDS TNLSQDALTM VRGYIGDNFG DKYLPATPNQ 360
  361 YSSKENSQEA HEAIRPSDVN VLAEQLKDME ADAQRLYQLI WRQFVACQMP PAKYDSTTLT 420
  421 VQAGDFQLRA KGRTLRFDGW TKVMPALRKG DEDRTLPVIE VGSDLDLQKL IPSQHFTKPP 480
  481 ARYSEASLVK ELEKRGIGRP STYASIISTI QDRGYVRVEN RRFYAEKMGE IVTDRLEENF 540
  541 RELMNYDFTA RMESGLDQVA NDQAEWKAVL DGFFAEFSEQ LEKAEKDPEE GGMRPNQMVM 600
  601 TSIDCPTCGR QMGIRTASTG VFLGCSGYAL PPKERCKTTI NLVPDAEILN ILEGDDAETN 660
  661 ALRARRRCQK CGTAMDSYLI DNQRKLHVCG NNPACDGYEI EAGEFRIKGY EGPIVECEKC 720
  721 GSEMHLKMGR FGKYMGCTND ECKNTRKILR SGEVAPPKED PVPLLELPCE KSDAYFVLRD 780
  781 GAAGVFLAAN TFPKSRETRA PLVEELVRFK DRLPEKLRYL ADAPVVDKEG NKTLVRFSRK 840
  841 TKQQYVSSEK DGKATGWSAF YIDGKWVEAK K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..590] PSI-BLAST 1000.0 AMINO TERMINAL 67KDA DOMAIN OF ESCHERICHIA COLI DNA TOPOISOMERASE I (RESIDUES 2-590 OF MATURE PROTEIN) CLONING ARTIFACT ADDS TWO RESIDUES TO THE AMINO-TERMINUS WHICH WERE NOT OBSERVED IN THE EXPERIMENTAL ELECTRON DENSITY (GLY-2, SER-1).
    2 View Details [591..753] FFAS03 1.24 No description for 2gaiA was found.
    3 View Details [754..871] PSI-BLAST 28.69897 C-TERMINAL DOMAIN OF ESCHERICHIA COLI TOPOISOMERASE I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA topoisomerase activity
    		•  10.2798831210729 bayes_pls_golite062009
  • DNA topoisomerase type I activity
    		•  8.04585827786358 bayes_pls_golite062009
  • isomerase activity
    		•  5.61256457337998 bayes_pls_golite062009
  • DNA binding
    		•  5.20730175008144 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.95671919332271 bayes_pls_golite062009
  • binding
    		•  4.3089127577748 bayes_pls_golite062009
  • catalytic activity
    		•  1.50449367975676 bayes_pls_golite062009
  • protein binding
    		•  0.377429709958808 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • DNA primase activity
    		•  5.9540205863426 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  3.28799371541043 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.10492296137226 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  2.95899525707851 bayes_pls_golite062009
  • RNA polymerase activity
    		•  2.95899525707851 bayes_pls_golite062009
  • binding
    		•  2.05994835507055 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.92096402764448 bayes_pls_golite062009
  • DNA binding
    		•  1.82925061950188 bayes_pls_golite062009
  • protein binding
    		•  0.557273506579609 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  0.47808023373242 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.453051411850154 bayes_pls_golite062009
  • catalytic activity
    		•  0.434839928397784 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.240481799431949 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle