YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: IGHG4

General Information:
Name(s) found: IGHG4 [HGNC (HUGO)]
Description(s) found:
Found 13 descriptions.
SHOW ALL
  • immunoglobulin heavy constant gamma 4 (G4m marker) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 327 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASTKGPSVFP LAPCSRSTSE STAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS  60
   61 GLYSLSSVVT VPSSSLGTKT YTCNVDHKPS NTKVDKRVES KYGPPCPSCP APEFLGGPSV 120
  121 FLFPPKPKDT LMISRTPEVT CVVVDVSQED PEVQFNWYVD GVEVHNAKTK PREEQFNSTY 180
  181 RVVSVLTVLH QDWLNGKEYK CKVSNKGLPS SIEKTISKAK GQPREPQVYT LPPSQEEMTK 240
  241 NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSRL TVDKSRWQEG 300
  301 NVFSCSVMHE ALHNHYTQKS LSLSLGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run HIR2 No Comments Green EM, et al (2005)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] PSI-BLAST 48.39794 Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma; Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma; Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antigen binding
    		•  6.15874156332332 bayes_pls_golite062009
  • peptide antigen binding
    		•  3.64034637674979 bayes_pls_golite062009
  • binding
    		•  1.98262954718581 bayes_pls_golite062009
  • receptor activity
    		•  1.9202781107236 bayes_pls_golite062009
  • receptor binding
    		•  1.67130413402976 bayes_pls_golite062009
  • IgG binding
    		•  1.6222936767122 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.50492718932189 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11174153927545 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11174153927545 bayes_pls_golite062009
  • immunoglobulin receptor activity
    		•  1.06402558628866 bayes_pls_golite062009
  • protein binding
    		•  0.925738463571838 bayes_pls_golite062009
  • immunoglobulin binding
    		•  0.48272957113121 bayes_pls_golite062009
  • cytokine binding
    		•  0.372406716355349 bayes_pls_golite062009
  • MHC class II receptor activity
    		•  0.251167772391909 bayes_pls_golite062009
  • growth factor binding
    		•  0.0566162403218091 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle