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Protein Overview: MMT2

General Information:
Name(s) found: MMT2 / YPL224C [SGD]
Description(s) found:
Found 18 descriptions.
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  • Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 449 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    integral to membrane [ISSLink to PubMed article]
    Biological Process: cellular iron ion homeostasis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRISIDSIK QFGSFVTGYN NTSYHAAGRA IRTSSLYSTM ISANPRRCLH SSKLLNKEGQ  60
   61 EEGYNEQLIS KMSSQNGSNS RQNESEGKKE GKASSVKSLL QHTHSHSHTH MHDNPLLSLN 120
  121 VQQIKKNPGV RITWIGLASN VGMAVGKFVG GITFHSQALL ADSVHALSDL VSDFLTLFSV 180
  181 QYASRKPTSE YPYGYGKVET VGSLAVSTIL AMAGISIGWS SLCAIVGPVI PHAILESMAG 240
  241 LIGETHSHSQ SLTQQATNVN AVWIAAGSIL VKEWVFQATK KVAIQTNSNV LMANAWHHRV 300
  301 DSLTSLVALV AITSSYFFNI QSLDNLGGLV VSGLIIKTGG QGILSSLKEL VDQSIPPTDP 360
  361 RYLEIESVIK DSIGSLKTDL DLKQSLHVRD LTILASGPNL RATTTLEVPV LHSGQEVGIR 420
  421 FLENAISTIR EDLRMKVPNV GRWTSSLLM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run NSE3 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] deduced N/A No confident structure predictions are available.
    2 View Details [117..449] Pfam 40.79588 Cation efflux family No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • cation transmembrane transporter activity
    		•  6.60087208506814 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  6.49419690808578 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  6.066906606566 bayes_pls_golite062009
  • transporter activity
    		•  4.27173462293249 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.19993137135137 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.18558383943492 bayes_pls_golite062009
  • efflux transmembrane transporter activity
    		•  2.65640147236 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.5985956122288 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.19343183150052 bayes_pls_golite062009
  • cation channel activity
    		•  2.19094036108769 bayes_pls_golite062009
  • ion channel activity
    		•  2.03125515494926 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.95530036989194 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.95111816239105 bayes_pls_golite062009
  • channel activity
    		•  1.95111816239105 bayes_pls_golite062009
  • binding
    		•  1.27456652114636 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.775439159437009 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.490905558612378 bayes_pls_golite062009
  • protein binding
    		•  0.311357063667067 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  0.255026640963499 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle