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Protein Overview: PSR1

General Information:
Name(s) found: PSR1 / YLL010C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 427 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed article]
    Biological Process: response to stress [IGILink to PubMed article]
    Molecular Function: phosphoprotein phosphatase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFISSILCC SSETTQSNSN SAYRQQQSSS LNKNRSVKHS NTKSRTRGVH QTNSPPSKTN  60
   61 SAATFSSTER STGKSGISTN DNEKKKPSSP TAAVTATTTN NMTKVEKRIS KDDLYEEKYE 120
  121 VDEDEEIDDE DNRRSRGIVQ EKGDAVKDTS RQKKQQQQQQ QQSQPQPQPQ SQSQSQSQSQ 180
  181 SQQRGPTVQV SSDHLIQDMN LSRVSSSSQA SETSNDADDE DDEDEEYIDL TLLQQGQYHA 240
  241 PGYNTLLPPQ DESTKGKKCL ILDLDETLVH SSFKYLRSAD FVLSVEIDDQ VHNVYVIKRP 300
  301 GVEEFLERVG KLFEVVVFTA SVSRYGDPLL DILDTDKVIH HRLFREACYN YEGNYIKNLS 360
  361 QIGRPLSDII ILDNSPASYI FHPQHAIPIS SWFSDTHDNE LLDIIPLLED LSVKTSLDVG 420
  421 KILDVTI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) PSR1 PSR2 WHI2
    View Details Krogan NJ, et al. (2006) PSR1 PSR2 VHS2 WHI2
    View Details Ho Y, et al. (2002) PSR1 WHI2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PSR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..225] MSA 46.142997 View MSA. No confident structure predictions are available.
    2 View Details [226..427] Pfam 98.769551 NLI interacting factor-like phosphatase No confident structure predictions are available.
    3 View Details [229..427] PSI-BLAST 69.0 No description for 2hhlA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle