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Protein Overview: AVT1

General Information:
Name(s) found: AVT1 / YJR001W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 602 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IMPLink to PubMed article]
    vacuole [IDALink to PubMed article]
    Biological Process: vacuolar transport [IMPLink to PubMed article]
    amino acid transport [IMPLink to PubMed article]
    Molecular Function: L-isoleucine transmembrane transporter activity [IMPLink to PubMed article]
    L-glutamine transmembrane transporter activity [IMPLink to PubMed article]
    transporter activity [ISSLink to PubMed article]
    L-tyrosine transmembrane transporter activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEQEPLSPN GRKRSEVHYI SIPLNRGSAF SPDDSVSQFQ SDGFMTRRQS ILDHPVGSFK  60
   61 GVNSLSRFAT SLRRANSFRN IELNADNERS FFKESNDETY DPDTLAPALD GRRLSVTLNN 120
  121 AGRPRITNLA NNDRVSTASM AIHDDDYGSI QNSTIGDSGS ILRPTASLTE MMSGGAGRRF 180
  181 TNNDMDSIVV KRVEGVDGKV VTLLAGQSTA PQTIFNSINV LIGIGLLALP LGLKYAGWVI 240
  241 GLTMLAIFAL ATFCTAELLS RCLDTDPTLI SYADLGYAAF GTKGRALISA LFTLDLLGSG 300
  301 VSLVILFGDS LNALFPQYST TFFKIVSFFI VTPPVFIPLS VLSNISLLGI LSTTGTVLVI 360
  361 CCCGLYKSSS PGSLVNPMET SMWPIDLKHL CLSIGLLSAC WGGHAVFPNL KTDMRHPDKF 420
  421 KDCLKTTYKI TSVTDIGTAV IGFLMFGNLV KDEITKNVLL TEGYPKFVYG LISALMTIIP 480
  481 IAKTPLNARP IVSVLDVLMN VQHIDEAASA IKRRAAKGLQ VFNRIFINVV FVLIAINFPE 540
  541 FDKIIAFLGA GLCFTICLIL PCWFYLRLCK TTIKPWERVA CHVTICISVV LSTLGVGAAI 600
  601 IS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AVT1 DOA4 MPC54 YEF1
    View Details Qiu et al. (2008) AVT1 AVT3 AVT4 AVT6 GAP1 VBA1 VBA2 VMA9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] deduced N/A No confident structure predictions are available.
    2 View Details [180..602] Pfam 126.130768 Transmembrane amino acid transporter protein No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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