Protein Overview: YHR202W

General Information:
Name(s) found:	YHR202W [SGD]
Description(s) found: Found 23 descriptions. SHOW ALL	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole, while HA-tagged protein is found in the soluble fraction, suggesting cytoplasmic localization [SGD]
Organism:	Saccharomyces cerevisiae
Length:	602 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] fungal-type vacuole [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILKLVHCLV ALTGLIFAKP YQQQQAVLAP SQDVPLRDIH IGDINFIHTT DTHGWLGSHL  60
   61 SQNDYDADWG DFVAFVDILR EKILRQSRDV IVIDTGDKRD GNGLSDATWP PGLRSSEIFN 120
  121 MMDYDLLTLG NHELYTAESA ILEYRGTSQS SKFKDKYVCS NVEFIEDDGT RVPFGNKYIT 180
  181 FETPIMKQRV LALSFLFSFQ RANNRAIVTP PLEEITQKSW FQNMVETNRE EEIDLIIVFG 240
  241 HLPATDPTER EMHKIHALIR KYYPNTVIQY FGGHTHIRDF VQLDSKSTCL QSGRFAETVG 300
  301 FLSINMTDPV DAESPIFSRR YIDFNKEAFK YHLSKLGHDS NVPVSTKKGK TISRLVNDLR 360
  361 HELNLNEKLG YIPQTYYVST RPLNSEENLY HLITHKILPN LIPPKNYEPS MSRFILINTG 420
  421 SVRYDLYKGP FTKDTEYIVM PFNNDWRFIT VPLVVASRVE TYLNKGPVIA SLGIPSSSHH 480
  481 KQHFGGFQKC PFINNPNLSE GYTTEDDFGC HGDDTPHNSQ REYDIPNVVQ CKEVKKVQEE 540
  541 EADPSKMVHV IFYSFMELDI LNAVNSIIND LGLRMENLTT NDCSHYGGDS TKKLLRDYFS 600
  601 QF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YGR160W	YHR202W	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YHR202W	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..362]	PSI-BLAST	135.54902	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
2	View Details	[363..602]	PSI-BLAST	135.54902	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
hydrolase activity	2.24146908837387	bayes_pls_golite062009
phosphoric ester hydrolase activity	1.03737380819929	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.923883943293703	bayes_pls_golite062009
phosphatase activity	0.887312719401347	bayes_pls_golite062009
catalytic activity	0.632097679642303	bayes_pls_golite062009
protein serine/threonine phosphatase activity	0.250303969391928	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.220522462289381	bayes_pls_golite062009
binding	0.0668837130631226	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2