YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: YHR202W
Organism: Saccharomyces cerevisiae
Length: 602 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHR202W.

Description E-value Query
Range
Subject
Range
NT5E - 5'-nucleotidase, ecto (CD73)
0.0 [20..570] [3..541]
YHR202W - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...
gi|190405977 - gi|190405977|gb|EDV09244.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|151944147 - gi|151944147|gb|EDN62440.1| conserved protein [Saccharomyces cerevisiae YJM789]
YH02_YEAST - Uncharacterized protein YHR202W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHR202W ...
0.0 [1..602] [1..602]
gi|254844958, gi... - gi|75830356|ref|ZP_00759636.1| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...
gi|75819525, gi|... - gi|75819525|ref|ZP_00749601.1| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...
gi|121630401, gi... - gi|75816852|ref|ZP_00747310.1| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...
5NTD_VIBCH - 5'-nucleotidase OS=Vibrio cholerae GN=nutA PE=3 SV=1
gi|227010187, gi... - gi|227082299|ref|YP_002810850.1| UDP-sugar hydrolase [Vibrio cholerae M66-2], gi|227010187|gb|ACP063...
gi|121548942, gi... - gi|121586775|ref|ZP_01676557.1| UDP-sugar hydrolase [Vibrio cholerae 2740-80], gi|121548942|gb|EAX58...
gi|153223519, gi... - gi|153223519|ref|ZP_01953921.1| UDP-sugar hydrolase [Vibrio cholerae MAK 757], gi|124118157|gb|EAY36...
gi|124122821, gi... - gi|153801644|ref|ZP_01956230.1| UDP-sugar hydrolase [Vibrio cholerae MZO-3], gi|124122821|gb|EAY4156...
gi|153818805, gi... - gi|153818805|ref|ZP_01971472.1| UDP-sugar hydrolase [Vibrio cholerae NCTC 8457], gi|126510648|gb|EAZ...
gi|254291405, gi... - gi|254291405|ref|ZP_04962198.1| UDP-sugar hydrolase [Vibrio cholerae AM-19226], gi|197751310|ref|YP_...
5NTD_VIBCH - 5'-nucleotidase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=nutA PE=...
0.0 [11..567] [5..539]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [20..570] [3..541]
5NTD_BOVIN - 5'-nucleotidase precursor (EC 3.1.3.5) (Ecto-5'-nucleotidase) (5'-NT) (CD73 antigen) - Bos taurus (B...
0.0 [18..570] [1..541]
gi|253976660, gi... - gi|254287353|ref|YP_003053101.1| UDP-sugar hydrolase [Escherichia coli BL21(DE3)], gi|253976660|gb|A...
gi|254160549, gi... - gi|254160549|ref|YP_003043657.1| UDP-sugar hydrolase [Escherichia coli B str. REL606], gi|253972450|...
EG11060 - bifunctional UDP-sugar hydrolase /5'-nucleotidase / UDP-glucose hydrolase, 5'-nucleotidase, CDP-alcoh...
USHA_ECOLI - Protein ushA precursor [Includes: UDP-sugar hydrolase (EC 3.6.1.45) (UDP-sugar diphosphatase) (UDP-s...
gi|169756060, gi... - gi|170021132|ref|YP_001726086.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precur...
gi|218425908, gi... - gi|218688344|ref|YP_002396556.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precur...
gi|170080065, gi... - gi|170080065|ref|YP_001729385.1| bifunctional UDP-sugar hydrolase and 5'-nucleotidase [Escherichia c...
gi|194423562, gi... - gi|83587065|ref|ZP_00925695.1| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...
gi|157157603, gi... - gi|75189548|ref|ZP_00702815.1| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...
gi|124499293, gi... - gi|124530268|ref|ZP_01700987.1| 5'-Nucleotidase domain protein [Escherichia coli B], gi|124499293|gb...
EG11060 - bifunctional UDP-sugar hydrolase /5'-nucleotidase / UDP-glucose hydrolase, 5'-nucleotidase, CDP-alcoh...
gi|75514603, gi|... - gi|75514603|ref|ZP_00736858.1| COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related e...
gi|89107349, gi|... - gi|89107349|ref|AP_001129.1| bifunctional UDP-sugar hydrolase and 5'-nucleotidase [Escherichia coli ...
gi|227884507, gi... - gi|227884507|ref|ZP_04002312.1| UDP-sugar diphosphatase [Escherichia coli 83972], gi|227838593|gb|EE...
gi|238899767, gi... - gi|238899767|ref|YP_002925563.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli ...
gi|242376261, gi... - gi|251783988|ref|YP_002998292.1| hypothetical protein B21_00436 [Escherichia coli BL21], gi|24237626...
0.0 [18..566] [8..535]
gi|757842 - gi|757842|emb|CAA27532.1| UDP-sugar hydrolase [Escherichia coli]
0.0 [18..566] [8..535]
gi|15829787, gi|... - gi|15829787|ref|NP_308560.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ...
gi|209397585, gi... - gi|209397585|ref|YP_002269131.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. ...
gi|208737316, gi... - gi|208823123|ref|ZP_03263441.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. E...
gi|208816167, gi... - gi|208816167|ref|ZP_03257346.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. E...
gi|208726870, gi... - gi|208807069|ref|ZP_03249406.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. E...
gi|217320999, gi... - gi|217324778|ref|ZP_03440862.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. T...
gi|209778288, gi... - pir||E90695 UDP-sugar diphosphatase (EC 3.6.1.45) precursor [similarity] - Escherichia coli (strain ...
gi|187769672, gi... - gi|187769672|gb|EDU33516.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC419...
gi|189362444, gi... - gi|189362444|gb|EDU80863.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC448...
gi|12513353, gi|... - gi|15800209|ref|NP_286221.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor ...
gi|168760363, gi... - gi|189369147|gb|EDU87563.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC450...
gi|15829787, gi|... - gi|15829787|ref|NP_308560.1| UDP-sugar hydrolase [Escherichia coli O157:H7], gi|13359990|dbj|BAB3395...
gi|168754587, gi... - gi|189357984|gb|EDU76403.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC440...
gi|195936043 - gi|195936043|ref|ZP_03081425.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precurs...
gi|168798046, gi... - gi|189379298|gb|EDU97714.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC508...
gi|168786334, gi... - gi|189373512|gb|EDU91928.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC869...
gi|168778976, gi... - gi|189003115|gb|EDU72101.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC407...
gi|168747842, gi... - gi|188017625|gb|EDU55747.1| UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC411...
gi|254591063, gi... - gi|254791663|ref|YP_003076500.1| bifunctional UDP-sugar hydrolase and 5'-nucleotidase [Escherichia c...
0.0 [18..566] [8..535]
5NTD_MOUSE - 5'-nucleotidase OS=Mus musculus GN=Nt5e PE=1 SV=2
0.0 [14..570] [11..543]
gi|194456120, gi... - gi|194469756|ref|ZP_03075740.1| protein UshA [Salmonella enterica subsp. enterica serovar Kentucky s...
gi|168818885, gi... - gi|205344064|gb|EDZ30828.1| protein UshA [Salmonella enterica subsp. enterica serovar Weltevreden st...
gi|6176420, gi|6... - gi|6176420|gb|AAF05578.1| UDP-sugar hydrolase [Salmonella enterica], gi|6176417|gb|AAF05575.1| UDP-s...
gi|195631837, gi... - gi|195631837|gb|EDX50357.1| protein UshA [Salmonella enterica subsp. enterica serovar Newport str. S...
gi|205334058, gi... - gi|205334058|gb|EDZ20822.1| protein UshA [Salmonella enterica subsp. enterica serovar Kentucky str. ...
gi|161364667, gi... - gi|161615303|ref|YP_001589268.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precur...
gi|238911376 - gi|238911376|ref|ZP_04655213.1| bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precurs...
0.0 [18..566] [8..535]

Back

Predicted Domain #1
Region A:
Residues: [1-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILKLVHCLV ALTGLIFAKP YQQQQAVLAP SQDVPLRDIH IGDINFIHTT DTHGWLGSHL  60
   61 SQNDYDADWG DFVAFVDILR EKILRQSRDV IVIDTGDKRD GNGLSDATWP PGLRSSEIFN 120
  121 MMDYDLLTLG NHELYTAESA ILEYRGTSQS SKFKDKYVCS NVEFIEDDGT RVPFGNKYIT 180
  181 FETPIMKQRV LALSFLFSFQ RANNRAIVTP PLEEITQKSW FQNMVETNRE EEIDLIIVFG 240
  241 HLPATDPTER EMHKIHALIR KYYPNTVIQY FGGHTHIRDF VQLDSKSTCL QSGRFAETVG 300
  301 FLSINMTDPV DAESPIFSRR YIDFNKEAFK YHLSKLGHDS NVPVSTKKGK TISRLVNDLR 360
  361 HE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 135.54902
Match: 1ush__
Description: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.24146908837387 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.03737380819929 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.923883943293703 bayes_pls_golite062009
phosphatase activity 0.887312719401347 bayes_pls_golite062009
catalytic activity 0.632097679642303 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.250303969391928 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.220522462289381 bayes_pls_golite062009
binding 0.0668837130631226 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [363-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNLNEKLGYI PQTYYVSTRP LNSEENLYHL ITHKILPNLI PPKNYEPSMS RFILINTGSV  60
   61 RYDLYKGPFT KDTEYIVMPF NNDWRFITVP LVVASRVETY LNKGPVIASL GIPSSSHHKQ 120
  121 HFGGFQKCPF INNPNLSEGY TTEDDFGCHG DDTPHNSQRE YDIPNVVQCK EVKKVQEEEA 180
  181 DPSKMVHVIF YSFMELDILN AVNSIINDLG LRMENLTTND CSHYGGDSTK KLLRDYFSQF 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 135.54902
Match: 1ush__
Description: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle