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Protein Overview: OTU2

General Information:
Name(s) found: OTU2 / YHL013C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGMESGENL ENMEDILARH RKENKDLQNK ITGMKKQATK SKRKEVNSKC LDLQDKLKTK  60
   61 QENEIRDWKI ANNEVFDAEQ EDEVTPEKLL EQLSISRDEK EQQNVPVQQQ QQGQTKKRRN 120
  121 RQKERLAKRD AAIAKMKEEA ALEASKQPDL KKMEQESIDQ LCELKKLKQF DIQPDGHCLF 180
  181 ASILDQLKLR HDPKKLDQDM DVMKLRWLSC NYVQEHRDDF IPYLFDEETM KMKDIDEYTK 240
  241 EMEHTAQWGG EIEILALSHV FDCPISILMS GRPIQVYNEC GKNPELKLVY YKHSYALGEH 300
  301 YNSLHDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data OTU2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] MSA 57.099997 View MSA. No confident structure predictions are available.
    2 View Details [172..307] Pfam 48.045757 OTU-like cysteine protease No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • structural molecule activity
    		•  2.83533458608428 bayes_pls_golite062009
  • peptidase activity
    		•  2.48902852150669 bayes_pls_golite062009
  • hydrolase activity
    		•  2.34555971384634 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.21975436249953 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.18854644194302 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.47306695258161 bayes_pls_golite062009
  • endopeptidase activity
    		•  1.38622772567128 bayes_pls_golite062009
  • catalytic activity
    		•  0.995453662223124 bayes_pls_golite062009
  • binding
    		•  0.805968129859542 bayes_pls_golite062009
  • protein binding
    		•  0.0907812929574578 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.0162117947236281 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle