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View Structure Prediction Details

Protein: OTU2
Organism: Saccharomyces cerevisiae
Length: 307 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OTU2.

Description E-value Query
Range
Subject
Range
gi|207344811 - gi|207344811|gb|EDZ71825.1| YHL013Cp-like protein [Saccharomyces cerevisiae AWRI1631]
OTU2 - Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ...
gi|151944188 - gi|151944188|gb|EDN62480.1| OTU family protein [Saccharomyces cerevisiae YJM789]
gi|190405770 - gi|190405770|gb|EDV09037.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
OTU2_YEAST - OTU domain-containing protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OTU2 PE=...
6.0E-60 [1..307] [1..307]
CG7857-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7857 (CG7857, FBgn0026738). It is a protein...
1.0E-47 [3..305] [10..309]
SPAC1952.03 - cysteine protease, OTU family
OTU2_SCHPO - Ubiquitin thioesterase otu2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=otu2 PE=3 SV=1
1.0E-46 [11..304] [23..319]
gi|5679842 - gi|5679842|emb|CAB51835.1| l1332.6 [Oryza sativa Indica Group]
gi|5679842, gi|1... - gi|90399337|emb|CAH68346.1| H0313F03.22 [Oryza sativa (indica cultivar-group)], gi|5679842|emb|CAB51...
2.0E-44 [7..305] [28..325]
gi|11358167, gi|... - gi|7573423|emb|CAB87739.1| putative protein [Arabidopsis thaliana], gi|21553607|gb|AAM62700.1| unkno...
1.0E-43 [2..305] [15..325]
CE03245 - Yeast YHB3-like protein status:Confirmed UniProt:Q19681 protein_id:CAA91033.1
3.0E-42 [4..303] [1..305]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGMESGENL ENMEDILARH RKENKDLQNK ITGMKKQATK SKRKEVNSKC LDLQDKLKTK  60
   61 QENEIRDWKI ANNEVFDAEQ EDEVTPEKLL EQLSISRDEK EQQNVPVQQQ QQGQTKKRRN 120
  121 RQKERLAKRD AAIAKMKEEA ALEASKQPDL KKMEQESIDQ LCELKKLKQF D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [172-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQPDGHCLFA SILDQLKLRH DPKKLDQDMD VMKLRWLSCN YVQEHRDDFI PYLFDEETMK  60
   61 MKDIDEYTKE MEHTAQWGGE IEILALSHVF DCPISILMSG RPIQVYNECG KNPELKLVYY 120
  121 KHSYALGEHY NSLHDS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 48.045757
Match: PF02338
Description: OTU-like cysteine protease

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
structural molecule activity 2.83533458608428 bayes_pls_golite062009
peptidase activity 2.48902852150669 bayes_pls_golite062009
hydrolase activity 2.34555971384634 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.21975436249953 bayes_pls_golite062009
cysteine-type peptidase activity 2.18854644194302 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.47306695258161 bayes_pls_golite062009
endopeptidase activity 1.38622772567128 bayes_pls_golite062009
catalytic activity 0.995453662223124 bayes_pls_golite062009
binding 0.805968129859542 bayes_pls_golite062009
protein binding 0.0907812929574578 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.0162117947236281 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle