YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: OTU2
Organism: Saccharomyces cerevisiae
Length: 307 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OTU2.

Description E-value Query
Range
Subject
Range
gi|207344811 - gi|207344811|gb|EDZ71825.1| YHL013Cp-like protein [Saccharomyces cerevisiae AWRI1631]
OTU2 - Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ...
gi|151944188 - gi|151944188|gb|EDN62480.1| OTU family protein [Saccharomyces cerevisiae YJM789]
gi|190405770 - gi|190405770|gb|EDV09037.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
OTU2_YEAST - OTU domain-containing protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OTU2 PE=...
6.0E-60 [1..307] [1..307]
CG7857-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7857 (CG7857, FBgn0026738). It is a protein...
1.0E-47 [3..305] [10..309]
SPAC1952.03 - cysteine protease, OTU family
OTU2_SCHPO - Ubiquitin thioesterase otu2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=otu2 PE=3 SV=1
1.0E-46 [11..304] [23..319]
gi|5679842 - gi|5679842|emb|CAB51835.1| l1332.6 [Oryza sativa Indica Group]
gi|5679842, gi|1... - gi|90399337|emb|CAH68346.1| H0313F03.22 [Oryza sativa (indica cultivar-group)], gi|5679842|emb|CAB51...
2.0E-44 [7..305] [28..325]
gi|11358167, gi|... - gi|7573423|emb|CAB87739.1| putative protein [Arabidopsis thaliana], gi|21553607|gb|AAM62700.1| unkno...
1.0E-43 [2..305] [15..325]
CE03245 - Yeast YHB3-like protein status:Confirmed UniProt:Q19681 protein_id:CAA91033.1
3.0E-42 [4..303] [1..305]

Back

Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGMESGENL ENMEDILARH RKENKDLQNK ITGMKKQATK SKRKEVNSKC LDLQDKLKTK  60
   61 QENEIRDWKI ANNEVFDAEQ EDEVTPEKLL EQLSISRDEK EQQNVPVQQQ QQGQTKKRRN 120
  121 RQKERLAKRD AAIAKMKEEA ALEASKQPDL KKMEQESIDQ LCELKKLKQF D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.399 0.461 cytoplasm d.19.1 MHC antigen-recognition domain
View Download 0.220 0.162 cytoplasm a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.227 0.047 cytoplasm a.47.1 STAT
View Download 0.213 0.045 cytoplasm a.25.1 Ferritin-like
View Download 0.242 0.025 cytoplasm a.126.1 Serum albumin-like

Predicted Domain #2
Region A:
Residues: [172-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQPDGHCLFA SILDQLKLRH DPKKLDQDMD VMKLRWLSCN YVQEHRDDFI PYLFDEETMK  60
   61 MKDIDEYTKE MEHTAQWGGE IEILALSHVF DCPISILMSG RPIQVYNECG KNPELKLVYY 120
  121 KHSYALGEHY NSLHDS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 48.045757
Match: PF02338
Description: OTU-like cysteine protease

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
structural molecule activity 2.83533458608428 bayes_pls_golite062009
peptidase activity 2.48902852150669 bayes_pls_golite062009
hydrolase activity 2.34555971384634 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.21975436249953 bayes_pls_golite062009
cysteine-type peptidase activity 2.18854644194302 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.47306695258161 bayes_pls_golite062009
endopeptidase activity 1.38622772567128 bayes_pls_golite062009
catalytic activity 0.995453662223124 bayes_pls_golite062009
binding 0.805968129859542 bayes_pls_golite062009
protein binding 0.0907812929574578 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.0162117947236281 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle