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Protein Overview: GLC3

General Information:
Name(s) found: GLC3 / YEL011W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 704 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: glycogen biosynthetic process [IMPLink to PubMed article]
    Molecular Function: 1,4-alpha-glucan branching enzyme activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNIPDNVKG AVEFDPWLKP FADVLSERRY LADKWLYDIT HATPDGSYQS LSKFARDSYK  60
   61 SYGLHANPET KEITYKEWAP NAERAFLVGD FNNWDTTSHE LKNKDEFGNF TITLHPLPNG 120
  121 DFAIPHDSKI KVMFILPDGS KIFRLPAWIT RATQPSKETS KQFGPAYEGR FWNPENPYKF 180
  181 VHPRPKFSES VDSLRIYEAH VGISSPEPKI TTYKEFTEKV LPRIKYLGYD AIQLMAIMEH 240
  241 AYYASFGYQV TNFFAASSRF GTPEELKELI DTAHSMGILV LLDVVHSHAS KNVEDGLNMF 300
  301 DGSDHQYFHS ISSGRGEHPL WDSRLFNYGK FEVQRFLLAN LAFYVDVYQF DGFRFDGVTS 360
  361 MLYVHHGVGA GGSFSGDYNE YLSRDRSFVD HEALAYLMLA NDLVHEMLPN LAVTVAEDVS 420
  421 GYPTLCLPRS IGGTGFDYRL AMALPDMWIK LIKEKKDDEW EMGSIVYTLT NRRYGEKVVA 480
  481 YCESHDQALV GDKTLAFWLM DAAMYTDMTV LKEPSIVIDR GIALHKMIRL ITHSLGGEAY 540
  541 LNFEGNEFGH PEWLDFPNVN NGDSYKYARR QFNLADDPLL RYQNLNEFDR SMQLCEKRHK 600
  601 WLNTKQAYVS LKHEGDKMIV FERNNLLFIF NFHPTNSYSD YRVGVEKAGT YHIVLNSDRA 660
  661 EFGGHNRINE SSEFFTTDLE WNNRKNFLQV YIPSRVALVL ALKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GLC3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 206.522879 Glycosyltrehalose trehalohydrolase, N-terminal domain N; Glycosyltrehalose trehalohydrolase; Glycosyltrehalose trehalohydrolase, central domain
    2 View Details [148..439] PSI-BLAST 206.522879 Glycosyltrehalose trehalohydrolase, N-terminal domain N; Glycosyltrehalose trehalohydrolase; Glycosyltrehalose trehalohydrolase, central domain
    3 View Details [440..628] PSI-BLAST 206.522879 Glycosyltrehalose trehalohydrolase, N-terminal domain N; Glycosyltrehalose trehalohydrolase; Glycosyltrehalose trehalohydrolase, central domain
    4 View Details [629..704] PSI-BLAST 100.751666 Cyclomaltodextrin glycanotransferase, domain D; Cyclodextrin glycosyltransferase, C-terminal domain; Cyclodextrin glycosyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, acting on glycosyl bonds
    		•  3.87554479203059 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  3.47174391073813 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • phosphorylase activity
    		•  0.99159540154441 bayes_pls_golite062009
  • glucosidase activity
    		•  0.766503513427695 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.763360027922833 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.687079660016821 bayes_pls_golite062009
  • sugar binding
    		•  0.52048704356718 bayes_pls_golite062009
  • chitinase activity
    		•  0.500233744020165 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.498330151821515 bayes_pls_golite062009
  • binding
    		•  0.391406996198514 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.31275257729319 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  0.263065978664289 bayes_pls_golite062009
  • hydrolase activity
    		•  0.15436539680525 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.0325030313870961 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.0325030313870961 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle