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Protein Overview: YHP1

General Information:
Name(s) found: YHP1 / YDR451C [SGD]
Description(s) found:
Found 29 descriptions.
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  • One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromosome [IDALink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article][IEPLink to PubMed article][IGILink to PubMed article][IPILink to PubMed article]
    regulation of transcription involved in G1/S-phase of mitotic cell cycle [IPILink to PubMed article]
    regulation of meiosis [IEPLink to PubMed article][IPILink to PubMed article]
    regulation of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: DNA binding [IDALink to PubMed article]
    specific transcriptional repressor activity [IDALink to PubMed article][IGILink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESRNTVLPS LPNIITGTSN SPFQLHTLPN TNFPSDDQGD IRLPPLAASA HIVRPVVNIY  60
   61 KSPCDEERPK RKSPQAVDFL SQRVTTSMTP LSKPKKLSSH SPFTPTVRVC SKEQPPQSMH 120
  121 SYKKVNILTP LSAAKAVLTP TTRKEKKRSF AFITHSQETF PKKEPKIDNA RLARRKRRRT 180
  181 SSYELGILQT AFDECPTPNK AKRIELSEQC NMSEKSVQIW FQNKRQAAKK HKNSGNTSHC 240
  241 KVHSNDSMSM ISYSDAALEI TSTPTSTKEA ITAELLKTSP ANTSSIFEDH HITPCKPGGQ 300
  301 LKFHRKSVLV KRTLSNTGHS EIIKSPKGKE NRLKFNAYER KPLGEVDLNS FKN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GET1 GET2 GET3 PSK1 TAT1 YHP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YHP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..157] MSA 14.759997 View MSA. No confident structure predictions are available.
    2 View Details [158..242] PSI-BLAST 77.502279 Paired protein
    3 View Details [243..353] MSA 2.190996 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle