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Protein Overview: EAF1

General Information:
Name(s) found: EAF1 / YDR359C [SGD]
Description(s) found:
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  • gi|849181|gb|AAB64794.1| Ydr359cp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S61155 hypothetical protein YDR359c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • VID21 - weak similarity to human trichohyalin [mips]
  • Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1 [SGD]
  • VID21, Chr IV from 1191995-1194874, reverse complement [yeast_orfs2]
  • Chr IV from 1191995-1194874, reverse complement [yeastorf3.fasta]
  • Chr IV from 1191994-1194873, reverse complement [yeastorf4.fasta]
  • Chr IV from 1194873-1191994, reverse complement [yeastorf5.fasta]
  • >Q06337 (Q06337) Chromosome IV COSMID 9476 [4932.FASTACCERV.txt]
  • hypothetical protein YDR359c - yeast (Saccharomyces cerevisiae)gi|849181|gb|AAB64794.1| Ydr359cp [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas]
  • (Q06337) Ydr359cp [cerv4932.FASTAC]
  • Ydr359cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 959 amino acids

    Gene Ontology:
    Cellular Component: NuA4 histone acetyltransferase complex [IPILink to PubMed articleLink to PubMed article]
    histone acetyltransferase complex [IPILink to PubMed article]
    Biological Process: chromatin modification [IPILink to PubMed article]
    DNA repair [IDALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRPSSAVP NSASLSEDQS SDRSKFPKAD DLIDERDRKL TELYCVSRLN QLLELTDENK  60
   61 LRKEIDAFLK KNDIRRGIRF DEASLPKLLH TAATPITKKK LKDVNLINVP NQRLSDSKMS 120
  121 RELPENSENV SVKSESHFVP SHDNSIRENM MDSLRPAEKT GGMWNKRPLE STMGGEEERH 180
  181 EKRQKMQSQS LESSNNSEMA SLPISPRPPV PNALAHYTYY ENIEYPPADP TEVQPAVKFK 240
  241 DPLIKNIMAK EIDTSDHYNE NNVDALETVF LLMNDYIPSK IPQALPLAEL KYMSQTLPLI 300
  301 NLIPRAHKAL TTNIINNALN EARITVVGSR IEELRRLGLW SLRQPKRFID PWKQHNTHQN 360
  361 ILLEEAKWMQ ADFKEGHKYK VAICTAMAQA IKDYWTYGEI CCVKRKTLLP GKENKLSDDG 420
  421 RISEKSGRPS DTSRNDSDIS IAGKDDIGII ANVDDITEKE SAAANDNDEN GKNEAGAKSD 480
  481 FDFADGLLSQ EGAHDQIISS IDTKLLLKKP SSSSEVVLIQ HEVAASSALI ETEESKKELA 540
  541 PPFKLSIFVD ELNTFEKTLI QDLPLYNGIN EERPKKDDSL PFIPISKSVV SLDDNGFYKL 600
  601 LERQLIDEEP SISQLSKRRG MFYGNRRNHY LRPPAVPSLR YLQNRTPTIW LSEDDQELVK 660
  661 NINTYGYNWE LISAHMTHRL TYSYLSNIER RTPWQCFERF VQLNERFNFS DLKGPRAHSA 720
  721 QQWLIEAHKF QQRQNRRISP LGVNTESIQR GHRRLRWASM FEAIRKCMKK RENTPRPNPT 780
  781 QPRKPLDCKN MKVPTPAEMS LLKAQRDEAL RRDIQLRRTV KNRLQQRQQQ SQQAHSSRAQ 840
  841 SPIPSNGKSS SNLARNGQAS APRPNQKQYT EQDIIESYSR KLLEQKPDIG PEMALKAAKN 900
  901 YYRTLREQQQ QLKQHQIQQQ RQQLQEESSH VQQLQQLQPG SSSSATEIIS ISIFSFQYF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SWC4 No Comments Hazbun TR, et al. (2003)
    View Run SWC4 No Comments Hazbun TR, et al. (2003)
    View Run ASF1 3829 - low filter Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..259] deduced N/A No confident structure predictions are available.
    2 View Details [260..406] MSA 4.006989 View MSA. No confident structure predictions are available.
    3 View Details [407..579] deduced N/A No confident structure predictions are available.
    4 View Details [580..840] MSA 1.002932 View MSA. No confident structure predictions are available.
    5 View Details [841..959] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle