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Protein Overview: RBS1

General Information:
Name(s) found: RBS1 / YDL189W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 457 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: galactose metabolic process [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTALDSRNWG LTPAMETGLF QKPQDRIFII ELENSIVSFI NSNTESFQLR PMNSYYRLLS  60
   61 HQIAEYHNLN HVLARTQDSC VILFKGENFQ KIEGKPLLQE LQLNKKPEEC ASSSESIEKS 120
  121 NNNRIFRILK RKEVGNECDY KIDGNTRTPN SNLTANSNKD QKIEIDDKSS TDLEQERIEK 180
  181 ERLYEQRKQE IFDKLNKSED DVKSTNSSGS SDSDNEWSDW LNGDDSNTQT SNGSVSSSSP 240
  241 FNSSVTTIQV NKPQQQFYDS RRGRGGRRRG TNNYKDAYRG QSRRNKENGG YQSGYSSPYL 300
  301 VYPPPQMGGN SLPTYPLMYN PAGPAPGPAP SPMVMGNNTV FMNPYMYNMN PQGSCSFGTP 360
  361 IPMYPPYQYQ YQYQYNTQYH SGPYSNTPSY NSNNYTRSSA NKYHHFQGKN SYSGAIPKRS 420
  421 DDSNSNKNEG IRRASVEGSP SSRDTDSVEM KFDKLNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run YNL313C No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RBS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 36.69897 Solution structure of the R3H domain from human hypothetical protein BAA76846
    2 View Details [159..277] deduced N/A No confident structure predictions are available.
    3 View Details [278..457] PSI-BLAST 3.09691 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.869425210311959 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.82872525437777 bayes_pls_golite062009
  • DNA binding
    		•  0.596936601153488 bayes_pls_golite062009
  • protein binding
    		•  0.520340792676972 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.371435369600675 bayes_pls_golite062009
  • catalytic activity
    		•  0.295853503406924 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle