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View Structure Prediction Details

Protein: RBS1
Organism: Saccharomyces cerevisiae
Length: 457 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBS1.

Description E-value Query
Range
Subject
Range
RBS1 - Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer...
240.0 [0..4] [457..35]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTALDSRNWG LTPAMETGLF QKPQDRIFII ELENSIVSFI NSNTESFQLR PMNSYYRLLS  60
   61 HQIAEYHNLN HVLARTQDSC VILFKGENFQ KIEGKPLLQE LQLNKKPEEC ASSSESIEKS 120
  121 NNNRIFRILK RKEVGNECDY KIDGNTRTPN SNLTANSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.69897
Match: 1whrA
Description: Solution structure of the R3H domain from human hypothetical protein BAA76846
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.869425210311959 bayes_pls_golite062009
nucleic acid binding 0.82872525437777 bayes_pls_golite062009
DNA binding 0.596936601153488 bayes_pls_golite062009
protein binding 0.520340792676972 bayes_pls_golite062009
transcription regulator activity 0.371435369600675 bayes_pls_golite062009
catalytic activity 0.295853503406924 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [159-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDQKIEIDDK SSTDLEQERI EKERLYEQRK QEIFDKLNKS EDDVKSTNSS GSSDSDNEWS  60
   61 DWLNGDDSNT QTSNGSVSSS SPFNSSVTTI QVNKPQQQFY DSRRGRGGRR RGTNNYKDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [278-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YRGQSRRNKE NGGYQSGYSS PYLVYPPPQM GGNSLPTYPL MYNPAGPAPG PAPSPMVMGN  60
   61 NTVFMNPYMY NMNPQGSCSF GTPIPMYPPY QYQYQYQYNT QYHSGPYSNT PSYNSNNYTR 120
  121 SSANKYHHFQ GKNSYSGAIP KRSDDSNSNK NEGIRRASVE GSPSSRDTDS VEMKFDKLNI 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle