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View Structure Prediction Details

Protein: RBS1
Organism: Saccharomyces cerevisiae
Length: 457 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBS1.

Description E-value Query
Range
Subject
Range
RBS1 - Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer...
240.0 [0..4] [457..35]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTALDSRNWG LTPAMETGLF QKPQDRIFII ELENSIVSFI NSNTESFQLR PMNSYYRLLS  60
   61 HQIAEYHNLN HVLARTQDSC VILFKGENFQ KIEGKPLLQE LQLNKKPEEC ASSSESIEKS 120
  121 NNNRIFRILK RKEVGNECDY KIDGNTRTPN SNLTANSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.69897
Match: 1whrA
Description: Solution structure of the R3H domain from human hypothetical protein BAA76846
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.869425210311959 bayes_pls_golite062009
nucleic acid binding 0.82872525437777 bayes_pls_golite062009
DNA binding 0.596936601153488 bayes_pls_golite062009
protein binding 0.520340792676972 bayes_pls_golite062009
transcription regulator activity 0.371435369600675 bayes_pls_golite062009
catalytic activity 0.295853503406924 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [159-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDQKIEIDDK SSTDLEQERI EKERLYEQRK QEIFDKLNKS EDDVKSTNSS GSSDSDNEWS  60
   61 DWLNGDDSNT QTSNGSVSSS SPFNSSVTTI QVNKPQQQFY DSRRGRGGRR RGTNNYKDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [278-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YRGQSRRNKE NGGYQSGYSS PYLVYPPPQM GGNSLPTYPL MYNPAGPAPG PAPSPMVMGN  60
   61 NTVFMNPYMY NMNPQGSCSF GTPIPMYPPY QYQYQYQYNT QYHSGPYSNT PSYNSNNYTR 120
  121 SSANKYHHFQ GKNSYSGAIP KRSDDSNSNK NEGIRRASVE GSPSSRDTDS VEMKFDKLNI 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle