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Protein Overview: PDX3

General Information:
Name(s) found: PDX3 / YBR035C [SGD]
Description(s) found:
Found 41 descriptions.
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  • Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 228 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    fatty acid metabolic process [IMPLink to PubMed article]
    Molecular Function: pyridoxamine-phosphate oxidase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKQAEETQK PIIFAPETYQ YDKFTLNEKQ LTDDPIDLFT KWFNEAKEDP RETLPEAITF  60
   61 SSAELPSGRV SSRILLFKEL DHRGFTIYSN WGTSRKAHDI ATNPNAAIVF FWKDLQRQVR 120
  121 VEGITEHVNR ETSERYFKTR PRGSKIGAWA SRQSDVIKNR EELDELTQKN TERFKDAEDI 180
  181 PCPDYWGGLR IVPLEIEFWQ GRPSRLHDRF VYRRKTENDP WKVVRLAP

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADH4 AGX1 AHA1 CDC33 CPR1 DUN1 HOM2 PDX3 PGM2 SOD1 TMA29 VMA4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139]
    [183..228]    		 PSI-BLAST 1311.69897 Pyridoxine 5'-phoshate oxidase (PNP oxidase)
    2 View Details [140..182] PSI-BLAST 1311.69897 Pyridoxine 5'-phoshate oxidase (PNP oxidase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyridoxamine-phosphate oxidase activity
    		•  3.81533880638523 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
    		•  1.18444956617957 bayes_pls_golite062009
  • catalytic activity
    		•  0.660906721832294 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.0268904833845668 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle