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Protein Overview: GYRB_ECOLI

General Information:
Name(s) found: GYRB_ECOLI [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • DNA gyrase subunit B (EC 5.99.1.3) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 804 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSYDSSSI KVLKGLDAVR KRPGMYIGDT DDGTGLHHMV FEVVDNAIDE ALAGHCKEII  60
   61 VTIHADNSVS VQDDGRGIPT GIHPEEGVSA AEVIMTVLHA GGKFDDNSYK VSGGLHGVGV 120
  121 SVVNALSQKL ELVIQREGKI HRQIYEHGVP QAPLAVTGET EKTGTMVRFW PSLETFTNVT 180
  181 EFEYEILAKR LRELSFLNSG VSIRLRDKRD GKEDHFHYEG GIKAFVEYLN KNKTPIHPNI 240
  241 FYFSTEKDGI GVEVALQWND GFQENIYCFT NNIPQRDGGT HLAGFRAAMT RTLNAYMDKE 300
  301 GYSKKAKVSA TGDDAREGLI AVVSVKVPDP KFSSQTKDKL VSSEVKSAVE QQMNELLAEY 360
  361 LLENPTDAKI VVGKIIDAAR AREAARRARE MTRRKGALDL AGLPGKLADC QERDPALSEL 420
  421 YLVEGDSAGG SAKQGRNRKN QAILPLKGKI LNVEKARFDK MLSSQEVATL ITALGCGIGR 480
  481 DEYNPDKLRY HSIIIMTDAD VDGSHIRTLL LTFFYRQMPE IVERGHVYIA QPPLYKVKKG 540
  541 KQEQYIKDDE AMDQYQISIA LDGATLHTNA SAPALAGEAL EKLVSEYNAT QKMINRMERR 600
  601 YPKAMLKELI YQPTLTEADL SDEQTVTRWV NALVSELNDK EQHGSQWKFD VHTNAEQNLF 660
  661 EPIVRVRTHG VDTDYPLDHE FITGGEYRRI CTLGEKLRGL LEEDAFIERG ERRQPVASFE 720
  721 QALDWLVKES RRGLSIQRYK GLGEMNPEQL WETTMDPESR RMLRVTVKDA IAADQLFTTL 780
  781 MGDAVEPRRA FIEENALKAA NIDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..394] PSI-BLAST 166.0 DNA gyrase B
    2 View Details [395..730] PSI-BLAST 66.30103 TOPOISOMERASE RESIDUES 410-1202,
    3 View Details [731..804] FFAS03 1.62 TOPOISOMERASE RESIDUES 410-1202,

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA topoisomerase activity
    		•  12.6906165486321 bayes_pls_golite062009
  • DNA topoisomerase (ATP-hydrolyzing) activity
    		•  11.8861942287485 bayes_pls_golite062009
  • isomerase activity
    		•  8.13079712911425 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.14522015372277 bayes_pls_golite062009
  • catalytic activity
    		•  2.10890475146569 bayes_pls_golite062009
  • protein kinase activity
    		•  1.84867054522487 bayes_pls_golite062009
  • kinase activity
    		•  1.68443268281997 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.64025200399404 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.60156177836014 bayes_pls_golite062009
  • DNA binding
    		•  1.5298919664856 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.38725999901881 bayes_pls_golite062009
  • binding
    		•  1.38505389441989 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.36270841743065 bayes_pls_golite062009
  • transferase activity
    		•  1.09369139087478 bayes_pls_golite062009
  • structural molecule activity
    		•  1.04534150109805 bayes_pls_golite062009
  • signal transducer activity
    		•  0.996368427522977 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.996368427522977 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.86218415868631 bayes_pls_golite062009
  • exonuclease activity
    		•  0.76163144715311 bayes_pls_golite062009
  • nuclease activity
    		•  0.42266682237543 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.0675296198098132 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.0671550940422005 bayes_pls_golite062009
    2
    Term Confidence Notes
  • DNA topoisomerase activity
    		•  16.1862836613251 bayes_pls_golite062009
  • DNA topoisomerase (ATP-hydrolyzing) activity
    		•  15.3845248199845 bayes_pls_golite062009
  • isomerase activity
    		•  11.5598219279347 bayes_pls_golite062009
  • DNA binding
    		•  4.42972615310468 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.21774496265744 bayes_pls_golite062009
  • binding
    		•  3.95084202265591 bayes_pls_golite062009
  • catalytic activity
    		•  1.83123392049501 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.17291817800492 bayes_pls_golite062009
  • protein binding
    		•  0.0229806746449869 bayes_pls_golite062009
    3
    Term Confidence Notes
  • DNA topoisomerase activity
    		•  15.4936903203186 bayes_pls_golite062009
  • DNA topoisomerase (ATP-hydrolyzing) activity
    		•  14.6489242328866 bayes_pls_golite062009
  • isomerase activity
    		•  11.0996144353545 bayes_pls_golite062009
  • DNA binding
    		•  4.07071788473104 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.8906242200463 bayes_pls_golite062009
  • binding
    		•  3.74481651990022 bayes_pls_golite062009
  • catalytic activity
    		•  1.68981384280236 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.95809415738291 bayes_pls_golite062009
  • protein binding
    		•  0.0435629034939063 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle