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Protein Overview: GCL_ECOLI

General Information:
Name(s) found: GCL_ECOLI [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Glyoxylate carboligase (EC 4.1.1.47) (Tartronate-semialdehyde synthase) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 593 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKMRAVDAA MYVLEKEGIT TAFGVPGAAI NPFYSAMRKH GGIRHILARH VEGASHMAEG  60
   61 YTRATAGNIG VCLGTSGPAG TDMITALYSA SADSIPILCI TGQAPRARLH KEDFQAVDIE 120
  121 AIAKPVSKMA VTVREAALVP RVLQQAFHLM RSGRPGPVLV DLPFDVQVAE IEFDPDMYEP 180
  181 LPVYKPAASR MQIEKAVEML IQAERPVIVA GGGVINADAA ALLQQFAELT SVPVIPTLMG 240
  241 WGCIPDDHEL MAGMVGLQTA HRYGNATLLA SDMVFGIGNR FANRHTGSVE KYTEGRKIVH 300
  301 IDIEPTQIGR VLCPDLGIVS DAKAALTLLV EVAQEMQKAG RLPCRKEWVA DCQQRKRTLL 360
  361 RKTHFDNVPV KPQRVYEEMN KAFGRDVCYV TTIGLSQIAA AQMLHVFKDR HWINCGQAGP 420
  421 LGWTIPAALG VCAADPKRNV VAISGDFDFQ FLIEELAVGA QFNIPYIHVL VNNAYLGLIR 480
  481 QSQRAFDMDY CVQLAFENIN SSEVNGYGVD HVKVAEGLGC KAIRVFKPED IAPAFEQAKA 540
  541 LMAQYRVPVV VEVILERVTN ISMGSELDNV MEFEDIADNA ADAPTETCFM HYE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..593] PSI-BLAST 156.0 Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide Chlorimuron Ethyl

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetolactate synthase activity
    		•  12.903449876837 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  12.3239025230705 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  5.28857071459273 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  5.21233670052586 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  5.08663245333808 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.51117258094456 bayes_pls_golite062009
  • transketolase activity
    		•  2.50501741089295 bayes_pls_golite062009
  • catalytic activity
    		•  2.25537597692103 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.15444163802756 bayes_pls_golite062009
  • DNA binding
    		•  2.09930834951157 bayes_pls_golite062009
  • deoxyhypusine synthase activity
    		•  2.04735838056767 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.00972611627502 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.98546381612935 bayes_pls_golite062009
  • NAD-dependent protein deacetylase activity
    		•  1.93141177609772 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity
    		•  1.93141177609772 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.91254869751164 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.90521776801103 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.85833680148029 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.82969293063325 bayes_pls_golite062009
  • 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
    		•  1.65348126142808 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  1.20517690263403 bayes_pls_golite062009
  • binding
    		•  1.17940168894417 bayes_pls_golite062009
  • transcription factor binding
    		•  1.07103864164531 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.0611726850452 bayes_pls_golite062009
  • transcription factor activity
    		•  1.0180828203704 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.982646671777 bayes_pls_golite062009
  • deacetylase activity
    		•  0.977680867213479 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.78591260444574 bayes_pls_golite062009
  • tartronate-semialdehyde synthase activity
    		•  0.591485766507531 bayes_pls_golite062009
  • hydrolase activity
    		•  0.536729211484905 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.516307124442946 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.51426028502998 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.42635585193838 bayes_pls_golite062009
  • transferase activity
    		•  0.413024577830522 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.23414654967509 bayes_pls_golite062009
  • pyruvate decarboxylase activity
    		•  0.198062360371269 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.114062221123972 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle