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Protein Overview: gi|25290765

General Information:
Name(s) found: gi|25290765 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • pir||F95125 ATP-dependent DNA helicase PcrA [imported] - Streptococcus pneumoniae (strain TIGR4) [NCBI NR]
    • Organism: Streptococcus pneumoniae
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNALLNGMND RQAEAVQTTE GPLLIMAGAG SGKTRVLTHR IAYLIDEKLV NPWNILAITF  60
   61 TNKAAREMKE RAYSLNPATQ DCLIATFHSM CVRILRRDAD HIGYNRNFTI VDPGEQRTLM 120
  121 KRILKQLNLD PKKWNERTIL GTISNAKNDL IDDVAYAAQA GDMYTQIVAQ CYTAYQKELR 180
  181 QSESVDFDDL IMLTLRLFDQ NPDVLTYYQQ KFQYIHVDEY QDTNHAQYQL VKLLASRFKN 240
  241 ICVVGDADQS IYGWRGADMQ NILDFEKDYP KAKVVLLEEN YRSTKTILQA ANEVIKNNKN 300
  301 RRPKNLWTQN ADGEQIVYYR ADDELDEAVF VARTIDELSR SQNFLHKDFA VLYRTNAQSR 360
  361 TIEEALLKSN IPYTMVGGTK FYSRKEIRDI IAYLNLIANL SDNISFERII NEPKRGIGLG 420
  421 TVEKIRDFAN LQNMSMLDAS ANIMLSGIKG KAAQSIWDFA NMMLDLREQL DHLSITELVE 480
  481 SVLEKTGYVD ILNSQATLES KARVENIEEF LSVTKNFDDT TDVTEEETGL DKLSRFLNDL 540
  541 ALIADTDSGS QETSEVTLMT LHAAKGLEFP VVFLIGMEEN VFPLSRATED SDELEEERRL 600
  601 AYVGITRAEK ILYLTNANSR LLFGRTNYNR PTRFINEISS DLLEYQGLAR PANTSFKASY 660
  661 SSGSISFGQG MSLAQALQDR KRGAAPKSIQ SSGLPFGQFT AGAKPASSEA NWSIGDIALH 720
  721 KKWGEGTVLE VSGSGARQEL KINFPEVGLK KLLASVAPIE KKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..763] PSI-BLAST 170.0 STRUCTURE OF DNA HELICASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.81138802583782 bayes_pls_golite062009
  • helicase activity
    		•  1.40781177352978 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.09000822067541 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.00391607739958 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.913322399315129 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.91290128595235 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.86836375892673 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.541554702463666 bayes_pls_golite062009
  • motor activity
    		•  0.50661339105747 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.390949264169589 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • DNA binding
    		•  0.376487324624615 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.133736530545575 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.11598665103566 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.95561462330096E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle