YRC Public Data Repository - Protein Structure Prediction

Protein:	YJCC_ECOLI
Organism:	Escherichia coli
Length:	528 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJCC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|88947158, gi\|... - gi\|88947158\|ref\|ZP_01150169.1\| PAS:GGDEF [Desulfotomaculum reducens MI-1], gi\|88923371\|gb\|EAR42405.1...	495.0	[0..54]	[514..469]
gi\|48859207, gi\|... - gi\|67875521\|ref\|ZP_00504817.1\| PAS:GGDEF [Clostridium thermocellum ATCC 27405], gi\|67850552\|gb\|EAM46...	488.0	[0..47]	[517..386]
gi\|89519310 - gi\|89519310\|gb\|ABD75787.1\| sensory box/GGDEF family protein [uncultured bacterium]	485.0	[0..56]	[521..409]
gi\|114332895, gi... - gi\|69949915\|ref\|ZP_00637879.1\| PAS:GGDEF [Shewanella frigidimarina NCIMB 400], gi\|69166539\|gb\|EAN755...	484.0	[0..27]	[522..995]
gi\|39997142, gi\|... - gi\|39997142\|ref\|NP_953093.1\| sensory box/GGDEF family protein [Geobacter sulfurreducens PCA], gi\|399...	482.0	[0..54]	[524..292]
gi\|78195532, gi\|... - gi\|78224277\|ref\|YP_386024.1\| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Geobacter...	482.0	[0..50]	[517..423]
gi\|24371939, gi\|... - gi\|24371939\|ref\|NP_715981.1\| sensory box protein [Shewanella oneidensis MR-1], gi\|24345777\|gb\|AAN534... SO0341 - sensory box protein	481.0	[0..27]	[519..1022]
gi\|78363780, gi\|... - gi\|78485494\|ref\|YP_391419.1\| diguanylate cyclase/phosphodiesterase [Thiomicrospira crunogena XCL-2],...	481.0	[0..51]	[519..1003]
gi\|68540985, gi\|... - gi\|68540985\|ref\|ZP_00580733.1\| PAS:GGDEF [Shewanella baltica OS155], gi\|68521370\|gb\|EAN44864.1\| PAS:...	481.0	[0..27]	[523..1018]
gi\|117919912, gi... - gi\|78687715\|ref\|ZP_00852455.1\| PAS:GGDEF [Shewanella sp. ANA-3], gi\|78504548\|gb\|EAP18101.1\| PAS:GGDE...	480.0	[0..32]	[526..946]

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Predicted Domain #1

Region A:
Residues: [1-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHRARHQLL ALPGIIFLVL FPIILSLWIA FLWAKSEVNN QLRTFAQLAL DKSELVIRQA  60
   61 DLVSDAAERY QGQVCTPAHQ KRMLNIIRGY LYINELIYAR DNHFLCSSLI APVNGYTIAP 120
  121 ADYKREPNVS IYYYRDTPFF SGYKMTYMQR GNYVAVINPL FWSEVMSDDP TLQWGVYDTV 180
  181 TKTFFSLSKE ASAATFSPLI HLKDLTVQRN GYLYATVYST KRPIAAIVAT SYQRLITHFY 240
  241 NHLIFALPAG ILGSLVLLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.0
Match:	1w25A
Description:	Response regulator PleD in complex with c-diGMP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
signal transducer activity	2.24109190514091	bayes_pls_golite062009
molecular transducer activity	2.24109190514091	bayes_pls_golite062009
transcription regulator activity	1.90779640471921	bayes_pls_golite062009
two-component response regulator activity	1.08011362874514	bayes_pls_golite062009
binding	0.284032791221831	bayes_pls_golite062009
nucleic acid binding	0.0177856074578452	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [260-528]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LWLRIRQNYL SPKRKLQRAL EKHQLCLYYQ PIIDIKTEKC IGAEALLRWP GEQGQIMNPA  60
   61 EFIPLAEKEG MIEQITDYVI DNVFRDLGDY LATHADRYVS INLSASDFHT SRLIARINQK 120
  121 TEQYAVRPQQ IKFEVTEHAF LDVDKMTPII LAFRQAGYEV AIDDFGIGYS NLHNLKSLNV 180
  181 DILKIDKSFV ETLTTHKTSH LIAEHIIELA HSLGLKTIAE GVETEEQVNW LRKRGVRYCQ 240
  241 GWFFAKAMPP QVFMQWMEQL PARELTRGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.69897
Match:	2r6oA
Description:	No description for 2r6oA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: