YRC Public Data Repository - Protein Structure Prediction

Protein:	RBSB_ECOLI
Organism:	Escherichia coli
Length:	296 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBSB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	293.0	[0..3]	[296..35]
gi\|20515183, gi\|... - gi\|20806727\|ref\|NP_621898.1\| transcriptional regulator [Thermoanaerobacter tengcongensis MB4], gi\|20... gi\|20806727 - gi\|20806727\|ref\|NP_621898.1\| Transcriptional regulator [Thermoanaerobacter tengcongensis MB4] gi\|254478068, gi... - gi\|254478068\|ref\|ZP_05091451.1\| Periplasmic binding proteins and sugar binding domain of the LacI fa...	292.0	[0..3]	[296..35]
gi\|76797419, gi\|... - gi\|76797419\|ref\|ZP_00779738.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti... gi\|241882990, gi... - gi\|241904637\|ref\|ZP_04789316.1\| transcriptional regulator, LacI family [Thermoanaerobacter brockii s...	284.0	[0..3]	[296..35]
gi\|51891908, gi\|... - gi\|51891908\|ref\|YP_074599.1\| LacI family transcriptional repressor [Symbiobacterium thermophilum IAM...	281.0	[0..3]	[295..32]
gi\|89209818, gi\|... - gi\|89209818\|ref\|ZP_01188212.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti...	277.0	[0..3]	[295..34]
gi\|90439667, gi\|... - gi\|90578834\|ref\|ZP_01234644.1\| putative transcriptional regulator, LacI family protein [Vibrio angus...	273.0	[0..4]	[296..34]

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Predicted Domain #1

Region A:
Residues: [1-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMKKLATLV SAVALSATVS ANAMAKDTIA LVVSTLNNPF FVSLKDGAQK EADKLGYNLV  60
   61 VLDSQNNPAK ELANVQDLTV RGTKILLINP TDSDAVGNAV KMANQANIPV ITLDRQATKG 120
  121 EVVSHIASDN VLGGKIAGDY IAKKAGEGAK VIELQGIAGT SAARERGEGF QQAVAAHKFN 180
  181 VLASQPADFD RIKGLNVMQN LLTAHPDVQA VFAQNDEMAL GALRALQTAG KSDVMVVGFD 240
  241 GTPDGEKAVN DGKLAATIAQ LPDQIGAKGV ETADKVLKGE KVQAKYPVDL KLVVKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.69897
Match:	1dbpA
Description:	IDENTICAL MUTATIONS AT CORRESPONDING POSITIONS IN TWO HOMOLOGOUS PROTEINS WITH NON-IDENTICAL EFFECTS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pentose transmembrane transporter activity	2.47679209577816	bayes_pls_golite062009
D-ribose transmembrane transporter activity	2.47679209577816	bayes_pls_golite062009
D-ribose-importing ATPase activity	2.47679209577816	bayes_pls_golite062009
monosaccharide-transporting ATPase activity	2.39566008731161	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	1.15685021131727	bayes_pls_golite062009
binding	1.13059008752468	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	0.53966958074777	bayes_pls_golite062009
transporter activity	0.399752289774857	bayes_pls_golite062009
transmembrane transporter activity	0.265529619623159	bayes_pls_golite062009
sugar transmembrane transporter activity	0.23981626136031	bayes_pls_golite062009
active transmembrane transporter activity	0.0415259877073471	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: