YRC Public Data Repository - Protein Structure Prediction

Protein:	GLPT_ECOLI
Organism:	Escherichia coli
Length:	452 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLPT_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	245.0	[0..6]	[448..1021]
gi\|91089229 - gi\|91089229\|ref\|XP_968302.1\| PREDICTED: similar to CG5304-PA [Tribolium castaneum]	245.0	[0..27]	[450..579]
gi\|67903516, gi\|... - gi\|67903516\|ref\|XP_682014.1\| hypothetical protein AN8745.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	235.0	[0..13]	[452..26]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	226.0	[0..2]	[438..424]
gi\|9657525, gi\|1... - gi\|9657525\|gb\|AAF96050.1\| glycerol-3-phosphate transporter [Vibrio cholerae O1 biovar eltor str. N16... gi\|11277446 - pir\|\|C82495 glycerol-3-phosphate transporter VCA0137 [imported] - Vibrio cholerae (strain N16961 ser...	219.0	[0..1]	[448..18]
gi\|226901081, gi... - gi\|237704715\|ref\|ZP_04535196.1\| sn-glycerol-3-phosphate transporter [Escherichia sp. 3_2_53FAA], gi\|... gi\|117624433, gi... - gi\|117624433\|ref\|YP_853346.1\| sn-glycerol-3-phosphate transporter [Escherichia coli APEC O1], gi\|115... gi\|218559156, gi... - gi\|218559156\|ref\|YP_002392069.1\| sn-glycerol-3-phosphate transporter [Escherichia coli S88], gi\|2183... gi\|91073106, gi\|... - gi\|91211532\|ref\|YP_541518.1\| sn-glycerol-3-phosphate transporter [Escherichia coli UTI89], gi\|910731...	217.0	[0..1]	[452..1]
gi\|119189209, gi... - gi\|90303997\|gb\|EAS33628.1\| hypothetical protein CIMG_04652 [Coccidioides immitis RS], gi\|119189209\|r...	216.0	[0..11]	[452..765]
gi\|82544516, gi\|... - gi\|82544516\|ref\|YP_408463.1\| sn-glycerol-3-phosphate transporter [Shigella boydii Sb227], gi\|8124592... gi\|209919692, gi... - gi\|209919692\|ref\|YP_002293776.1\| sn-glycerol-3-phosphate transporter [Escherichia coli SE11], gi\|209... gi\|215487456, gi... - gi\|215487456\|ref\|YP_002329887.1\| sn-glycerol-3-phosphate transporter [Escherichia coli O127:H6 str. ... gi\|75177961, gi\|... - gi\|75177961\|ref\|ZP_00698023.1\| COG2271: Sugar phosphate permease [Shigella boydii BS512], gi\|1877330... gi\|26109032, gi\|... - gi\|26248627\|ref\|NP_754667.1\| sn-glycerol-3-phosphate transporter [Escherichia coli CFT073], gi\|26109... gi\|190909586, gi... - gi\|75243054\|ref\|ZP_00726760.1\| COG2271: Sugar phosphate permease [Escherichia coli F11], gi\|19117007... gi\|110642447, gi... - gi\|110642447\|ref\|YP_670177.1\| sn-glycerol-3-phosphate transporter [Escherichia coli 536], gi\|1103440... gi\|74312762, gi\|... - gi\|74312762\|ref\|YP_311181.1\| sn-glycerol-3-phosphate transporter [Shigella sonnei Ss046], gi\|7385623... gi\|157156117, gi... - gi\|75187029\|ref\|ZP_00700296.1\| COG2271: Sugar phosphate permease [Escherichia coli E24377A], gi\|1571... gi\|157161723, gi... - gi\|75196281\|ref\|ZP_00706351.1\| COG2271: Sugar phosphate permease [Escherichia coli HS], gi\|157161723... gi\|253974152, gi... - gi\|254162251\|ref\|YP_003045359.1\| sn-glycerol-3-phosphate transporter [Escherichia coli B str. REL606... gi\|253323881, gi... - gi\|254289012\|ref\|YP_003054760.1\| sn-glycerol-3-phosphate transporter [Escherichia coli BL21(DE3)], g... gi\|251785601, gi... - gi\|251785601\|ref\|YP_002999905.1\| hypothetical protein B21_02125 [Escherichia coli BL21], gi\|24237787... gi\|227887297, gi... - gi\|227887297\|ref\|ZP_04005102.1\| sn-glycerol-3-phosphate transporter [Escherichia coli 83972], gi\|227... gi\|218554803, gi... - gi\|218554803\|ref\|YP_002387716.1\| sn-glycerol-3-phosphate transporter [Escherichia coli IAI1], gi\|218... gi\|218690402, gi... - gi\|218690402\|ref\|YP_002398614.1\| sn-glycerol-3-phosphate transporter [Escherichia coli ED1a], gi\|218... gi\|218352578, gi... - gi\|218695846\|ref\|YP_002403513.1\| sn-glycerol-3-phosphate transporter [Escherichia coli 55989], gi\|21...	216.0	[0..1]	[452..1]
gi\|208807023, gi... - gi\|208807023\|ref\|ZP_03249360.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC42... gi\|208812109, gi... - gi\|208812109\|ref\|ZP_03253438.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC40... gi\|208739886, gi... - gi\|208819763\|ref\|ZP_03260083.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC40... gi\|209396305, gi... - gi\|209396305\|ref\|YP_002271649.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4... gi\|189372863, gi... - gi\|189372863\|gb\|EDU91279.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC869], ... gi\|168798406, gi... - gi\|189378956\|gb\|EDU97372.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC508], ... gi\|209765488, gi... - pir\|\|G85863 sn-glycerol-3-phosphate permease [imported] - Escherichia coli (strain O157:H7, substrai... gi\|170518011, gi... - gi\|170680293\|ref\|YP_001744437.1\| glycerol-3-phosphate transporter [Escherichia coli SMS-3-5], gi\|170... gi\|195935616 - gi\|195935616\|ref\|ZP_03080998.1\| sn-glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. E... gi\|15802789, gi\|... - gi\|15802789\|ref\|NP_288816.1\| sn-glycerol-3-phosphate transporter [Escherichia coli O157:H7 EDL933], ... gi\|189368223, gi... - gi\|189368223\|gb\|EDU86639.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4501],... gi\|13362595, gi\|... - gi\|15832379\|ref\|NP_311152.1\| sn-glycerol-3-phosphate permease [Escherichia coli O157:H7], gi\|1336259... gi\|168767862, gi... - gi\|189362858\|gb\|EDU81277.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4486],... gi\|187771260, gi... - gi\|187771260\|gb\|EDU35104.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4196],... gi\|189001894, gi... - gi\|189001894\|gb\|EDU70880.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4076],... gi\|168749645, gi... - gi\|188016107\|gb\|EDU54229.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4113],... gi\|13362595, gi\|... - gi\|15832379\|ref\|NP_311152.1\| sn-glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. Saka... gi\|217319508, gi... - gi\|217327141\|ref\|ZP_03443224.1\| glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. TW14... gi\|254593533, gi... - gi\|254794133\|ref\|YP_003078970.1\| sn-glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. ... gi\|218700712, gi... - gi\|218700712\|ref\|YP_002408341.1\| sn-glycerol-3-phosphate transporter [Escherichia coli IAI39], gi\|21...	216.0	[0..1]	[452..1]
gi\|194424956, gi... - gi\|83588226\|ref\|ZP_00926851.1\| COG2271: Sugar phosphate permease [Escherichia coli 101-1], gi\|194436...	216.0	[0..1]	[452..1]

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Predicted Domain #1

Region A:
Residues: [1-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSIFKPAPH KARLPAAEID PTYRRLRWQI FLGIFFGYAA YYLVRKNFAL AMPYLVEQGF  60
   61 SRGDLGFALS GISIAYGFSK FIMGSVSDRS NPRVFLPAGL ILAAAVMLFM GFVPWATSSI 120
  121 AVMFVLLFLC GWFQGMGWPP CGRTMVHWWS QKERGGIVSV WNCAHNVGGG IPPLLFLLGM 180
  181 AWFNDWHAAL YMPAFCAILV ALFAFAMMRD TPQSCGLPPI EEYKNDYPDD YNEKAEQELT 240
  241 AKQIFMQYVL PNKLLWYIAI ANVFVYLLRY GILDWSPTYL KEVKHFALDK SSWAYFLYEY 300
  301 AGIPGTLLCG WMSDKVFRGN RGATGVFFMT LVTIATIVYW MNPAGNPTVD MICMIVIGFL 360
  361 IYGPVMLIGL HALELAPKKA AGTAAGFTGL FGYLGGSVAA SAIVGYTVDF FGWDGGFMVM 420
  421 IGGSILAVIL LIVVMIGEKR RHEQLLQERN GG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.522879
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glucose-6-phosphate transmembrane transporter activity	8.42101508058771	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	8.42101508058771	bayes_pls_golite062009
glycerol transmembrane transporter activity	7.11654923455995	bayes_pls_golite062009
alcohol transmembrane transporter activity	6.7545566917184	bayes_pls_golite062009
polyol transmembrane transporter activity	6.7545566917184	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	6.56587510931539	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.46247398538901	bayes_pls_golite062009
ion transmembrane transporter activity	4.58978526526921	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
anion transmembrane transporter activity	3.94605227012838	bayes_pls_golite062009
cation transmembrane transporter activity	3.88180006470231	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	3.5078894802599	bayes_pls_golite062009
organic anion transmembrane transporter activity	3.3413526350788	bayes_pls_golite062009
cation:sugar symporter activity	2.99050613058546	bayes_pls_golite062009
sugar:hydrogen symporter activity	2.99050613058546	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	2.62141276633776	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	2.52916479889426	bayes_pls_golite062009
sugar transmembrane transporter activity	2.47557586092261	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
solute:hydrogen symporter activity	2.10485633822652	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
binding	1.26757615356623	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
organophosphate:inorganic phosphate antiporter activity	0.796599261179881	bayes_pls_golite062009
glycerol-phosphate:inorganic phosphate antiporter activity	0.796599261179881	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
phosphate transmembrane transporter activity	0.312628600969375	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: