YRC Public Data Repository - Protein Structure Prediction

Protein:	SO1197
Organism:	Shewanella oneidensis
Length:	649 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SO1197.

Description	E-value	Query Range	Subject Range
FTSH_SALTI - Cell division protease ftsH OS=Salmonella typhi GN=hflB PE=3 SV=1 FTSH_SALTY - Cell division protease ftsH OS=Salmonella typhimurium GN=hflB PE=3 SV=1 gi\|214000933 - gi\|214000933\|ref\|ZP_03411668.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|224585091, gi... - gi\|224585091\|ref\|YP_002638890.1\| cell division protein [Salmonella enterica subsp. enterica serovar ... gi\|56129482, gi\|... - gi\|56415225\|ref\|YP_152300.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|238910089 - gi\|238910089\|ref\|ZP_04653926.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|207858544, gi... - gi\|207858544\|ref\|YP_002245195.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|213052988 - gi\|213052988\|ref\|ZP_03345866.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... lcl\|NC_016856.1_... - [gene=hflB] [protein=ATP-dependent metalloprotease] [protein_id=YP_005239474.1] [location=complement... gi\|213425426 - gi\|213425426\|ref\|ZP_03358176.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|213852786 - gi\|213852786\|ref\|ZP_03382318.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|29143547, gi\|... - gi\|29143547\|ref\|NP_806889.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|160867488, gi... - gi\|161506141\|ref\|YP_001573253.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. arizonae ... FTSH_SALTY - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhimurium GN=ftsH PE=3 SV=1 gi\|16762058 - gi\|16762058\|ref\|NP_457675.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|161616303, gi... - gi\|161616303\|ref\|YP_001590268.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... FTSH_SALTI - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhi GN=ftsH PE=3 SV=1 gi\|197364155, gi... - gi\|197364155\|ref\|YP_002143792.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... FTSH_SALTY - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7007... gi\|205273978, gi... - gi\|205354197\|ref\|YP_002227998.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ...	592.0	[0..1]	[638..1]
gi\|205357195, gi... - gi\|205357195\|ref\|ZP_02345811.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|197248059, gi... - gi\|197248059\|ref\|YP_002148220.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|195873641, gi... - gi\|195873641\|ref\|ZP_02697399.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194471603, gi... - gi\|194471603\|ref\|ZP_03077587.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194447870, gi... - gi\|194447870\|ref\|YP_002047324.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|194442507, gi... - gi\|194442507\|ref\|YP_002042552.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|205348591, gi... - gi\|205360607\|ref\|ZP_02684667.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205343557, gi... - gi\|205359745\|ref\|ZP_02831638.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205359196, gi... - gi\|205359196\|ref\|ZP_02668061.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|62181804, gi\|... - gi\|62181804\|ref\|YP_218221.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|205333758, gi... - gi\|205358490\|ref\|ZP_02656962.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente...	592.0	[0..1]	[638..4]
gi\|37528354, gi\|... - gi\|37528354\|ref\|NP_931699.1\| ATP-dependent metalloprotease [Photorhabdus luminescens subsp. laumondi...	586.0	[0..1]	[633..4]
gi\|746401 - gi\|746401\|gb\|AAA97508.1\| ATP-binding protein gi\|188487047, gi... - gi\|188491848\|ref\|ZP_02999118.1\| ATP-dependent metallopeptidase HflB [Escherichia coli 53638], gi\|188... gi\|157068341, gi... - gi\|157162661\|ref\|YP_001459979.1\| ATP-dependent metalloprotease [Escherichia coli HS], gi\|157068341\|g... gi\|157080734, gi... - gi\|157158704\|ref\|YP_001464653.1\| ATP-dependent metalloprotease [Escherichia coli E24377A], gi\|157080... gi\|226839967, gi... - gi\|254038343\|ref\|ZP_04872401.1\| ATP-dependent metalloprotease [Escherichia sp. 1_1_43], gi\|226839967... gi\|253771988, gi... - gi\|253771988\|ref\|YP_003034819.1\| ATP-dependent metalloprotease FtsH [Escherichia coli BL21(DE3)], gi... gi\|237706070, gi... - gi\|237706070\|ref\|ZP_04536551.1\| ATP-dependent metalloprotease [Escherichia sp. 3_2_53FAA], gi\|226899... gi\|194411725, gi... - gi\|194430224\|ref\|ZP_03062722.1\| ATP-dependent metallopeptidase HflB [Escherichia coli B171], gi\|1944... tr\|A0A0G3HSQ2\|A0... - ATP-dependent zinc metalloprotease FtsH OS=Escherichia coli (strain K12) GN=ftsH PE=3 SV=1 gi\|191168060, gi... - gi\|191168060\|ref\|ZP_03029860.1\| ATP-dependent metallopeptidase HflB [Escherichia coli B7A], gi\|19090...	585.0	[0..1]	[638..4]
gi\|218555748, gi... - gi\|218555748\|ref\|YP_002388661.1\| ATP-dependent metalloprotease [Escherichia coli IAI1], gi\|218362516... gi\|218358002, gi... - gi\|218550461\|ref\|YP_002384252.1\| ATP-dependent metalloprotease [Escherichia fergusonii ATCC 35469], ... gi\|218429032, gi... - gi\|218691468\|ref\|YP_002399680.1\| ATP-dependent metalloprotease [Escherichia coli ED1a], gi\|218429032... gi\|218367017, gi... - gi\|218560248\|ref\|YP_002393161.1\| ATP-dependent metalloprotease [Escherichia coli S88], gi\|218367017\|... gi\|218701947, gi... - gi\|218701947\|ref\|YP_002409576.1\| ATP-dependent metalloprotease [Escherichia coli IAI39], gi\|21837193... gi\|218696883, gi... - gi\|218696883\|ref\|YP_002404550.1\| ATP-dependent metalloprotease [Escherichia coli 55989], gi\|21835361... gi\|218706798, gi... - gi\|218706798\|ref\|YP_002414317.1\| ATP-dependent metalloprotease [Escherichia coli UMN026], gi\|2184338... FTSH_ECOLI - Cell division protease ftsH (EC 3.4.24.-) - Escherichia coli EG11506 - protease, ATP-dependent zinc-metallo / ATP-dependent membrane protease, complexed with HflCK; regula... FTSH_SHIFL - ATP-dependent zinc metalloprotease FtsH OS=Shigella flexneri GN=ftsH PE=3 SV=1 gi\|24053649, gi\|... - gi\|24114467\|ref\|NP_708977.1\| ATP-dependent metalloprotease [Shigella flexneri 2a str. 301], gi\|24053... gi\|30042775, gi\|... - gi\|30064516\|ref\|NP_838687.1\| ATP-dependent metalloprotease [Shigella flexneri 2a str. 2457T], gi\|300... EG11506 - protease, ATP-dependent zinc-metallo / ATP-dependent membrane protease, complexed with HflCK; regula... gi\|227887899, gi... - gi\|227887899\|ref\|ZP_04005704.1\| M41 family endopeptidase FtsH [Escherichia coli 83972], gi\|227835295... gi\|238863291, gi... - gi\|238902280\|ref\|YP_002928076.1\| protease, ATP-dependent zinc-metallo [Escherichia coli BW2952], gi\|... gi\|251786448, gi... - gi\|251786448\|ref\|YP_003000752.1\| hypothetical protein B21_02994 [Escherichia coli BL21], gi\|24237872... gi\|253975021, gi... - gi\|254163120\|ref\|YP_003046228.1\| protease, ATP-dependent zinc-metallo [Escherichia coli B str. REL60... gi\|253979177, gi... - gi\|254289870\|ref\|YP_003055618.1\| protease, ATP-dependent zinc-metallo [Escherichia coli BL21(DE3)], ... gi\|169890548, gi... - gi\|170082713\|ref\|YP_001732033.1\| subunit of integral membrane ATP-dependent zinc metallopeptidase [E... gi\|169753500, gi... - gi\|170018572\|ref\|YP_001723526.1\| ATP-dependent metalloprotease [Escherichia coli ATCC 8739], gi\|1697... gi\|215266566, gi... - gi\|215488494\|ref\|YP_002330925.1\| ATP-dependent metalloprotease [Escherichia coli O127:H6 str. E2348/... gi\|209920653, gi... - gi\|209920653\|ref\|YP_002294737.1\| ATP-dependent metalloprotease [Escherichia coli SE11], gi\|209913912... gi\|75197127 - gi\|75197127\|ref\|ZP_00707197.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli HS] gi\|75208502 - gi\|75208502\|ref\|ZP_00708822.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli B171] gi\|75187984 - gi\|75187984\|ref\|ZP_00701251.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli E24377A] gi\|146028, gi\|89... - gi\|89109941\|ref\|AP_003721.1\| protease, ATP-dependent zinc-metallo [Escherichia coli str. K-12 substr... gi\|91074173, gi\|... - gi\|91212599\|ref\|YP_542585.1\| ATP-dependent metalloprotease [Escherichia coli UTI89], gi\|91074173\|gb\|... gi\|117625472, gi... - gi\|117625472\|ref\|YP_858795.1\| ATP-dependent metalloprotease [Escherichia coli APEC O1], gi\|115514596... gi\|110345010, gi... - gi\|110643418\|ref\|YP_671148.1\| ATP-dependent metalloprotease [Escherichia coli 536], gi\|110345010\|gb\|... gi\|75228765 - gi\|75228765\|ref\|ZP_00715374.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli B7A] gi\|110616592, gi... - gi\|110807044\|ref\|YP_690564.1\| ATP-dependent metalloprotease [Shigella flexneri 5 str. 8401], gi\|1106... gi\|74313715, gi\|... - gi\|74313715\|ref\|YP_312134.1\| ATP-dependent metalloprotease [Shigella sonnei Ss046], gi\|73857192\|gb\|A...	585.0	[0..1]	[638..1]
gi\|82778492, gi\|... - gi\|82778492\|ref\|YP_404841.1\| ATP-dependent metalloprotease [Shigella dysenteriae Sd197], gi\|81242640...	585.0	[0..1]	[638..1]
FTSH_ECO57 - ATP-dependent zinc metalloprotease FtsH OS=Escherichia coli O157:H7 GN=ftsH PE=3 SV=1 gi\|13363530, gi\|... - gi\|15833311\|ref\|NP_312084.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 str. Sakai], gi... gi\|254594527, gi... - gi\|254795127\|ref\|YP_003079964.1\| subunit of integral membrane ATP-dependent zinc metallopeptidase [E... gi\|209758260, gi... - pir\|\|D85981 cell division protein HflB/FtsH proteinase [imported] - Escherichia coli (strain O157:H7... gi\|209160879, gi... - gi\|209399479\|ref\|YP_002272648.1\| ATP-dependent metallopeptidase HflB [Escherichia coli O157:H7 str. ... gi\|195938397 - gi\|195938397\|ref\|ZP_03083779.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 str. EC4024] gi\|15803718, gi\|... - gi\|15803718\|ref\|NP_289752.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 EDL933], gi\|125... gi\|217319989, gi... - gi\|217327622\|ref\|ZP_03443705.1\| ATP-dependent metallopeptidase HflB [Escherichia coli O157:H7 str. T...	585.0	[0..1]	[638..1]
gi\|75240799 - gi\|75240799\|ref\|ZP_00724697.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli F11]	585.0	[0..1]	[638..1]
gi\|81246995, gi\|... - gi\|82545584\|ref\|YP_409531.1\| ATP-dependent metalloprotease [Shigella boydii Sb227], gi\|81246995\|gb\|A...	585.0	[0..1]	[638..1]
gi\|78691964, gi\|... - gi\|78691964\|ref\|ZP_00856547.1\| Peptidase M41, FtsH [Shewanella sp. MR-7], gi\|78508641\|gb\|EAP22080.1\|...	580.0	[0..1]	[649..9]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKNLILWVV IAVVLMSVFQ GYSPSSSSSQ KMDYSTFLDN VRDGQVATVE VKSDQRTIEG  60
   61 SKRTGEKFTT IMPLYDQDLI NDLDRKGITM KGQEAEESGF LTQIFISWFP MLLLIGVWIF 120
  121 FMRQMQGGGG KGAMSFGKSK A

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	26.075721
Match:	PF06480.6
Description:	No description for PF06480.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [142-649]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLMSEDQIKT TFADVAGCDE AKEEVKELVD YLRDPTKFQK LGGRIPTGVL MVGPPGTGKT  60
   61 LLAKAIAGES KVPFFTISGS DFVEMFVGVG ASRVRDMFEQ AKKSAPCIIF IDEIDAVGRQ 120
  121 RGAGLGGGHD EREQTLNQML VEMDGFEGNE GIIVIAATNR PDVLDSALLR PGRFDRQVVV 180
  181 GLPDVRGREQ ILKVHMRKVP LSEDVKASVI ARGTPGFSGA DLANLVNEAA LFAARGNRRV 240
  241 VGMEEFERAK DKIMMGAERR SMVMSEAEKE MTAYHEAGHA IVGCLVPEHD PVHKVTIIPR 300
  301 GRALGVTFFL PEADAISQSR RKLESQISVA YGGRLAEELI YGTEKVSTGA SQDIKYATSI 360
  361 ARNMVTQWGF SDKLGPLLYA EEEGEVFLGR SMGKAKAMSD ETATLIDTEV KAFIDKNYSR 420
  421 AKQILQDNVD ILHSMKDALM KYETIDSLQI DDLMNRREVR QPADWQADEN GSNDKGNGKG 480
  481 EPAVKVDEVV KSAPAEAELK DADESPVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	111.0
Match:	2ce7A
Description:	EDTA treated
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.37825960678081	bayes_pls_golite062009
binding	1.31163400557981	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
GTPase activity	0.69051700701659	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.489050800152752	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.485303203507997	bayes_pls_golite062009
pyrophosphatase activity	0.482413717607895	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.457886666766291	bayes_pls_golite062009
purine nucleotide binding	0.428373955572763	bayes_pls_golite062009
purine ribonucleotide binding	0.424644011903671	bayes_pls_golite062009
ribonucleotide binding	0.424583288440993	bayes_pls_golite062009
nucleotide binding	0.422354428195324	bayes_pls_golite062009
peptidase activity	0.0753480171639475	bayes_pls_golite062009
ATP binding	0.04834397972685	bayes_pls_golite062009
adenyl ribonucleotide binding	0.0149501427627318	bayes_pls_golite062009
adenyl nucleotide binding	0.00365326483311895	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: