YRC Public Data Repository - Protein Structure Prediction

Protein:	ACCC_ECOLI
Organism:	Escherichia coli
Length:	449 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACCC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|91774335, gi\|... - gi\|91774335\|ref\|YP_567027.1\| pyruvate carboxylase subunit A [Methanococcoides burtonii DSM 6242], gi...	551.0	[0..1]	[443..1]
gi\|83636689, gi\|... - gi\|83648646\|ref\|YP_437081.1\| acetyl-CoA carboxylase, biotin carboxylase [Hahella chejuensis KCTC 239...	539.0	[0..1]	[444..1]
gi\|83858502, gi\|... - gi\|83858502\|ref\|ZP_00952024.1\| acetyl-CoA carboxylase [Oceanicaulis alexandrii HTCC2633], gi\|8385332...	535.0	[0..1]	[448..1]
gi\|56383850, gi\|... - gi\|56480299\|ref\|NP_709051.2\| acetyl-CoA carboxylase biotin carboxylase subunit [Shigella flexneri 2a...	533.0	[0..1]	[449..1]
gi\|94495479, gi\|... - gi\|94495479\|ref\|ZP_01302059.1\| acetyl-CoA carboxylase, biotin carboxylase [Sphingomonas sp. SKA58], ...	532.0	[0..2]	[448..3]
gi\|120556352, gi... - gi\|77953092\|ref\|ZP_00817503.1\| Acetyl-CoA carboxylase, biotin carboxylase [Marinobacter aquaeolei VT...	531.0	[0..1]	[444..3]
gi\|78711946, gi\|... - gi\|78778447\|ref\|YP_396559.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Prochlorococcus mari...	531.0	[0..1]	[444..1]
gi\|49474255, gi\|... - gi\|49474255\|ref\|YP_032297.1\| acetyl-CoA carboxylase biotin carboxylase subunit [Bartonella quintana ...	530.0	[0..1]	[447..1]
gi\|254246384, gi... - gi\|84356763\|ref\|ZP_00981599.1\| COG0439: Biotin carboxylase [Burkholderia cenocepacia PC184], gi\|2542...	530.0	[0..1]	[449..1]
gi\|39997117, gi\|... - gi\|39997117\|ref\|NP_953068.1\| acetyl-CoA carboxylase, biotin carboxylase [Geobacter sulfurreducens PC...	529.0	[0..1]	[442..1]

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Predicted Domain #1

Region A:
Residues: [1-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDKIVIANR GEIALRILRA CKELGIKTVA VHSSADRDLK HVLLADETVC IGPAPSVKSY  60
   61 LNIPAIISAA EITGAVAIHP GYGFLSENAN FAEQVERSGF IFIGPKAETI RLMGDKVSAI 120
  121 AAMKKAGVPC VPGSDGPLGD DMDKNRAIAK RIGYPVIIKA SGGGGGRGMR VVRGDAELAQ 180
  181 SISMTRAEAK AAFSNDMVYM EKYLENPRHV EIQVLADGQG NAIYLAERDC SMQRRHQKVV 240
  241 EEAPAPGITP ELRRYIGERC AKACVDIGYR GAGTFEFLFE NGEFYFIEMN TRIQVEHPVT 300
  301 EMITGVDLIK EQLRIAAGQP LSIKQEEVHV RGHAVECRIN AEDPNTFLPS PGKITRFHAP 360
  361 GGFGVRWESH IYAGYTVPPY YDSMIGKLIC YGENRDVAIA RMKNALQELI IDGIKTNVDL 420
  421 QIRIMNDENF QHGGTNIHYL EKKLGLQEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	147.0
Match:	2gpsA
Description:	No description for 2gpsA was found.

Predicted functions:

Term	Confidence	Notes
acetyl-CoA carboxylase activity	7.97944928068929	bayes_pls_golite062009
CoA carboxylase activity	7.26031530137805	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	7.11064677387039	bayes_pls_golite062009
biotin carboxylase activity	6.9547407447638	bayes_pls_golite062009
ligase activity	6.37416374794432	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	4.25267317906061	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	4.17451795830682	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.99262646198755	bayes_pls_golite062009
phosphoribosylaminoimidazole carboxylase activity	1.57708889650281	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1.11645327303429	bayes_pls_golite062009
catalytic activity	1.08688404807699	bayes_pls_golite062009
phosphoribosylamine-glycine ligase activity	1.04915286326924	bayes_pls_golite062009
acid-amino acid ligase activity	0.730894973410499	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	0.695070201354335	bayes_pls_golite062009
glutathione synthase activity	0.0685848191991462	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: