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View Structure Prediction Details

Protein: fpn-1.1
Organism: Caenorhabditis elegans
Length: 509 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fpn-1.1.

Description E-value Query
Range
Subject
Range
gi|125974406, gi... - gi|67916575|ref|ZP_00510280.1| Amino acid adenylation [Clostridium thermocellum ATCC 27405], gi|6784...
197.0 [0..6] [384..1380]

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Predicted Domain #1
Region A:
Residues: [1-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWLSGKELQ LNSAFLLTTL GDRMWAFVIG LFMHQLGGMT WVAVQQLVDS VLKLVVITIV  60
   61 GQYLDKIDRS KIIQRTLLLN NAAVAVSAGL FAYMFVHKTD HYATPVLLMA SAVASIAKVA 120
  121 SEIQRISFTK DWVVVISQSE SVDLAKVNSI LLCIDQISSA ILPTLTGELL DTFKWQYVCG 180
  181 FIIVYNLASW VIESMILRRL YNETPQLKTR ASEITGDEEL RGLKGVKLNS ITQYFKQQSW 240
  241 TAGFGLSLLY MTVLGFDNLA ASYGQKHGLS ASYIGVLRGF GSALGVIGTF SFQFVAKRFG 300
  301 LLWTVMIGLV WQNIFIEMCG VSVLLPGSSM DVSGYIANTS VSEWSKEVLS RVSNPEPQNV 360
  361 PSVSFYDVAL PVNLFFIGIS FARFGLWLAD PAITQIQQET IPESQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.26757615356623 bayes_pls_golite062009
anion transmembrane transporter activity 1.24023641504332 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.05725800478022 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [406-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYMAFTVQIA LNEVFSILKD IIVIMFPFTP LFGVLTLGSC VFVFTGFMFN VFYHAQCGFS  60
   61 CVNKNMHLGR QPVCEMATLS SPEKQSLMGD EKEKPKVLDS PTFE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle