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View Structure Prediction Details

Protein: LKHA4_ARATH
Organism: Arabidopsis thaliana
Length: 616 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LKHA4_ARATH.

Description E-value Query
Range
Subject
Range
gi|68368751 - gi|68368751|ref|XP_684042.1| PREDICTED: similar to Aminopeptidase puromycin sensitive [Danio rerio]
491.0 [0..1] [604..270]

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Predicted Domain #1
Region A:
Residues: [1-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPIDPHSFT DSSHPLTTHV ALSLYLDFNT SIIHGSALLT LSSAFSGELS LDTRCISIAM  60
   61 VLDPLTLEPI PYSVSTTPDR IRGTEVVVVL SGQSSLLIVY STSPSASALQ WLSPLQTFSK 120
  121 LHPYVYTQCQ AIHARSIFPC QDTPAARIRY DVVMNIPNSL SAVMSARHVR RRLAVPEEAK 180
  181 HLEAGSLGSS LWCGEDRVVE EFAMEQPIPP YLFAFAVGEL GFREVGPRTR VYTESAAIEV 240
  241 LDAAALEFAG TEDMIKQGEK LFGDYEWERF DLLVLPPSFP YGGMENPRMV FLTPTVIKGD 300
  301 ATGAQVVAHE LAHSWTGNLI TNINNEHFWL NEGFTTYAER RIVEVVQGAD IATLNIGIGW 360
  361 RGLTDEMERF KDNLECTKLW NKQEGVDPDD VYSQVPYEKG FQFVLRIERQ IGRTAFDEFL 420
  421 KKYIATFKFK SIDTNTFLEF LKANIPGIEK EINLQLWTEG VGIPEDAYEP VSTIYTKIIS 480
  481 LAKEFKEGKM PSEDDVAEWN GQEWELYLEN LPKSCEPSQV MALDKRYRLA ESKDYEVKVS 540
  541 FLQLAVTSKC REYHGEVKKT LKEVGRMKYL RPLFTALAQS GGTEEKQLAK QVFAEARETY 600
  601 HPIAQGVVES ILSKYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.0
Match: 1gw6A
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.71606469379318 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.36548300377296 bayes_pls_golite062009
endopeptidase activity 2.68178232987479 bayes_pls_golite062009
hydrolase activity 2.4180994157249 bayes_pls_golite062009
metallopeptidase activity 2.1215666797696 bayes_pls_golite062009
metalloendopeptidase activity 1.55964119804062 bayes_pls_golite062009
binding 1.29310089768477 bayes_pls_golite062009
nucleic acid binding 1.00618489031368 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
exopeptidase activity 0.364756038518376 bayes_pls_golite062009
protein binding 0.278366242068789 bayes_pls_golite062009
aminopeptidase activity 0.21808506596674 bayes_pls_golite062009
transcription regulator activity 0.0671277591944419 bayes_pls_golite062009
DNA binding 0.0559585284546991 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle