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View Structure Prediction Details

Protein: gi|6728986, gi|1...
Organism: Arabidopsis thaliana
Length: 479 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6728986, gi|1....

Description E-value Query
Range
Subject
Range
SYHC_ORYSJ - Histidine--tRNA ligase, cytoplasmic OS=Oryza sativa subsp. japonica GN=Os05g0150900 PE=2 SV=2
SYH_ORYSA - Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS) - Oryza sativa (Rice)
318.0 [0..7] [477..318]

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Predicted Domain #1
Region A:
Residues: [1-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSLMQCGEQ ILNLFNPEGR SFDSLLDKVK EIVESNENRR LPKLPKGTRD FAKEQMAVRE  60
   61 KAFSIIQNVF KRHGATALDT PVFELRETLM GKYGEDSKLV YDIADQGGEL CSLRYDLTVP 120
  121 FARYVAMNGI TSFKRYQIAK VYRRDNPSKG RYREFYQCDF DIAGLFEPMG PDFEIVKILT 180
  181 ELLDELEIGD YEVKLNHRKL LDGMLEICGV PPEKFRTICS SIDKLDKQSF EQVKKEMVEE 240
  241 KGLSSEIADR IGNFVKEKGA PLELLSKLRQ EGSEFLDNQS SREALDELSI MFEALKRSKC 300
  301 SERIVFDLSL ARGLDYYTGV IFEAVCIGAE VGSIGAGGRY DNLIGMFGTK QVPAVGMSLG 360
  361 IERVFNIMEE LNEKQKQVIR PTETQVLVSI MVDNKLAEAA ELVSQLWGAK INAEYLVSKR 420
  421 KEKHFNRAKE SGIPWMVMVG EKELSGSFVT LKKLEKGSEE KEDQTCTRDR FVEELKKLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.30103
Match: 1kmmA
Description: Histidyl-tRNA synthetase (HisRS), C-terminal domain; Histidyl-tRNA synthetase (HisRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.89468709683036 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.89468709683036 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.88410036819636 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
histidine-tRNA ligase activity 5.91343220471745 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 2.99105702052936 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
binding 0.521863822270226 bayes_pls_golite062009
transcription regulator activity 0.375542987753806 bayes_pls_golite062009
nucleic acid binding 0.281662799812287 bayes_pls_golite062009
DNA binding 0.0309732052586011 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle