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View Structure Prediction Details

Protein: SYTM1_ARATH
Organism: Arabidopsis thaliana
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYTM1_ARATH.

Description E-value Query
Range
Subject
Range
gi|3617770, gi|1... - gi|3617770|emb|CAA74705.1| threonyl-tRNA synthetase [Arabidopsis thaliana], pir||T51624 threonine-tR...
524.0 [0..1] [709..1]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRLTARSI RRFTTSSSSL PLLSSSSFCT VPTMAANHPK DEAYLSAVIP KRIKLFEQIQ  60
   61 ANQLENLKSL PHD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1vj7A
Description: Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [74-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIKVTLPDGN VKEGKKWETT PMDIAAQISK GLANSALISA VDDVLWDMNR PLEGDCKLEL  60
   61 FKFDSDKGRD TLWHSSAHIL GQALEQEYGC QLCIGPCTTR GEGFYYDGFY GELGLSDNHF 120
  121 PSIEAGAAKA AKEAQPFERI EVTKDQALEM FSENNFKVEL INGLPADMTI TVYRCGPLVD 180
  181 LCRGPHIPNT SFVKAFKCLR ASSAYWKGDK DRESLQRVYG ISYPDQKQLK KYLQFLEEAK 240
  241 KYDHRLLGQK QELFFSHQLS PGSYFFLPLG TRVYNRLMDF IKNQYWHRGY TEVITPNMYN 300
  301 MELWQTSGHA DNYKDNMFTF NIEKQEFGLK PMNCPGHCLI FQHRVRSYRE LPMRLADFGV 360
  361 LHRNEASGAL SGLTRVRRFQ QDDAHIFCTT EQVKGEVQGV LEFIDYVYKV FGFTYELKLS 420
  421 TRPEKYLGDL ETWDKAEADL KEAIEAFGKP LVLNEGDGAF YGPKIDITVS DAMNRKFQCA 480
  481 TLQLDFQLPI RFNLEYAAED EAKKSRPVMI HRAVLGSVER MFAILLEHYK GKWPFWISPR 540
  541 QAIVCPISEK SQQYAEKVQK QIKDAGFYVD ADLTDRKIDK KVREAQLAQY NYILVVGETE 600
  601 AATGQVSVRV RDNAAHSVKS IEDLLEEFKA KTAEFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 138.0
Match: 1qf6A
Description: Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.89468709683036 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.89468709683036 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.88410036819636 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
threonine-tRNA ligase activity 6.47381405106149 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 2.99105702052936 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
binding 1.11470390774037 bayes_pls_golite062009
transcription regulator activity 1.0753492604686 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
nucleic acid binding 0.897558352141977 bayes_pls_golite062009
DNA binding 0.854148126675211 bayes_pls_golite062009
transcription repressor activity 0.55217603492525 bayes_pls_golite062009
transcription factor activity 0.283508546234551 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle