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View Structure Prediction Details

Protein: G6PD3_ARATH
Organism: Arabidopsis thaliana
Length: 599 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for G6PD3_ARATH.

Description E-value Query
Range
Subject
Range
gi|22654991, gi|... - gi|27764952|gb|AAO23597.1| At1g24280/F3I6_22 [Arabidopsis thaliana], gi|22654991|gb|AAM98087.1| At1g...
815.0 [0..1] [599..1]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSCPTYR SRTSSSSPFL SNHHHSSLIN VVDPRRSLSF HYASPQGLNL AELCVVRSQR  60
   61 RSVQSSVVVQ DGSVATESSS SEEAKDVGVL TIPSLEADKV VAESDGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [108-599]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQLSTVSITV VGASGDLAKK KIFPALFALY YEGCLPEHFT IFGYARSKMT DAELRVMVSK  60
   61 TLTCRIDKRA NCGEKMEEFL KRCFYHSGQY DSQEHFVALD EKLKEHEGGR LSNRLFYLSI 120
  121 PPNIFVDAVK CASSSASSVN GWTRVIVEKP FGRDSKTSAA LTKSLKQYLE EDQIFRIDHY 180
  181 LGKELVENLS VLRFSNLIFE PLWSRQYIRN VQFIFSEDFG TEGRGGYFDN YGIIRDIMQN 240
  241 HLLQILALFA METPVSLDAE DIRNEKVKVL RSMRPIKLED VVIGQYKSHS IGGVTYPSYT 300
  301 DDKTVPKGSL TPTFAAAALF IDNARWDGVP FLMKAGKALN TRSAEIRVQF RHVPGNLYNR 360
  361 NSGTDRDQTT NELVIRVQPD EAIYLKINNK VPGLGMRLDQ SNLNLLYSAR YSKEIPDAYE 420
  421 RLLLDAIEGE RRLFIRSDEL DAAWALFTPL LKEIEEKKTT PEFYPYGSRG PVGAHYLAAK 480
  481 HKVQWGDLSL DQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1qkiA
Description: Glucose 6-phosphate dehydrogenase, N-terminal domain; Glucose 6-phosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glucose-6-phosphate dehydrogenase activity 5.10379236186634 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
steroid dehydrogenase activity 1.75109362865449 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.55012034958204 bayes_pls_golite062009
DNA binding 1.30649176474402 bayes_pls_golite062009
nucleic acid binding 1.21797427723368 bayes_pls_golite062009
retinol dehydrogenase activity 1.16811519855038 bayes_pls_golite062009
transcription regulator activity 1.16624046427845 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
binding 0.982999356179965 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.749202992278132 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.65743456407889 bayes_pls_golite062009
transcription factor activity 0.64823933426147 bayes_pls_golite062009
hydrolase activity 0.64282074902621 bayes_pls_golite062009
transcription repressor activity 0.547377529205729 bayes_pls_golite062009
NAD or NADH binding 0.44922383360529 bayes_pls_golite062009
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity 0.375786741986945 bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 0.362878028601961 bayes_pls_golite062009
coenzyme binding 0.35922330382799 bayes_pls_golite062009
structural molecule activity 0.34148076461528 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.225978107187737 bayes_pls_golite062009
kinase activity 0.201113035937958 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.156723490409668 bayes_pls_golite062009
glucose binding 0.13030486887358 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.126337510738706 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.111651152766906 bayes_pls_golite062009
protein kinase activity 0.0808301652371467 bayes_pls_golite062009
cation transmembrane transporter activity 0.0244314674300794 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle