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Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Acc: GO:0030604
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis.
Synonyms:
  • 1-deoxyxylulose-5-phosphate reductoisomerase activity
  • 1-deoxy-D-xylulose-5-phosphate isomeroreductase activity
  • DXP-reductoisomerase activity
  • DOXP reductoisomerase activity
  • 2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)
  • 2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030604 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity (interactive image map)
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