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View Structure Prediction Details

Protein: dli-1
Organism: Caenorhabditis elegans
Length: 443 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dli-1.

Description E-value Query
Range
Subject
Range
gi|60422784 - gi|60422784|gb|AAH89794.1| Dync1li2 protein [Rattus norvegicus]
385.0 [0..1] [443..1]

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Predicted Domain #1
Region A:
Residues: [1-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPTAQPLEF DDTANAVLPV LYSSTDEEVG IWRELLASKK TNTNQGSTVI VLGDNRSGKS  60
   61 SLLSRLDKSD RTVKPKSLLG YRVLHVQNDA RDASYAYQLG TAGANLNPSE LLQIPVWSLD 120
  121 GNAACASLLK HALPATPAEA IFILTASIDN PNLIHSLKRW ANVCTEQAQK HFTKEDLKAG 180
  181 RSQQEKMWQE YVDPVQSQMS TSVVGSFADE HNLLPLDQGT LTENCGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.69897
Match: 2folA
Description: Crystal structure of human RAB1A in complex with GDP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
plus-end-directed microtubule motor activity 3.89478272344579 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.9316157348091 bayes_pls_golite062009
pyrophosphatase activity 2.85508132376901 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.83578652703908 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.83259287122192 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
transporter activity 2.54024930442614 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.3671333448422 bayes_pls_golite062009
transmembrane transporter activity 2.35987232569028 bayes_pls_golite062009
ATPase activity, coupled 2.15516086601295 bayes_pls_golite062009
binding 2.01755875920323 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
hydrolase activity 1.55579437761895 bayes_pls_golite062009
microfilament motor activity 1.28029120876672 bayes_pls_golite062009
substrate-specific transporter activity 1.26618119830599 bayes_pls_golite062009
purine nucleotide binding 0.912853112793192 bayes_pls_golite062009
nucleotide binding 0.905342574142397 bayes_pls_golite062009
purine ribonucleotide binding 0.904115761720541 bayes_pls_golite062009
ribonucleotide binding 0.904053997411779 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.877711904204486 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
active transmembrane transporter activity 0.403546959736573 bayes_pls_golite062009
ATP binding 0.38929752840764 bayes_pls_golite062009
adenyl ribonucleotide binding 0.364108656344062 bayes_pls_golite062009
adenyl nucleotide binding 0.356069365520539 bayes_pls_golite062009
ion transmembrane transporter activity 0.328995639437459 bayes_pls_golite062009
primary active transmembrane transporter activity 0.264741960233164 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.252628307425696 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.191104435852081 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.190037546554641 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.189653398557061 bayes_pls_golite062009
GTPase activity 0.105546189348878 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [228-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFMVVITKSD LVLGKEFTDA QFAKISIQLR KFCLSLGATL VFTSAKETKN IQLLQKYIVH  60
   61 RSFGTAFTSA AQVIERESIF VPAGWDGEKK IDIIRESIPD VDSALEPTRD KLRPVAKEQL 120
  121 IEAEEDQAFL KKLMDILATS TTTAAPKPRT MQEEPTDKDS PLANFFSNLL NKDKPSKVSS 180
  181 PSTVSQPMDA AATQAQLDRL LKSAQSPKPQ PRDSDA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle